Tele-Pulmonary Rehabilitation for Chronic Lung Diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized study compares a supervised remote tele-rehabilitation program to standard in-person pulmonary rehabilitation among adults with COPD, ILD, bronchiectasis, or PAH in Israel. Ninety participants from two medical centers will be followed for 12 months to measure initiation and adherence to rehabilitation, safety, symptoms, and quality of life. Data are collected through ongoing remote monitoring, periodic interviews, and validated questionnaires to assess respiratory symptoms, mood, knowledge, and satisfaction. The trial aims to determine if tele-rehabilitation can reduce barriers to access and improve patient outcomes compared with traditional care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients meeting the Israeli Health Basket criteria for reimbursement of pulmonary rehabilitation (PR), including one of the following conditions:

   * COPD with an FEV1 below 50% or with severe exacerbation (hospitalization) in the previous year or two moderate exacerbations in the previous year.
   * Interstitial lung disease with an FVC below 80% or a DLCO below 60%.
   * Bronchiectasis with at least two exacerbations in the past year or at least one hospitalization, and an FEV1 below 80%.
   * Pulmonary arterial hypertension.
2. Willingness to initiate a PR or Tele-PR (TPR) programs.
3. Ability to perform the TPR program or traditional PR activities as assessed by a member of the study team prior to enrollment.
4. Agree to participate, with signed informed consent.

Exclusion Criteria:

1. Uncontrolled comorbidity (e.g uncontrolled congestive heart failure)
2. Inability to operate the mobile application.
3. Without a mobile device or computer.
4. A hospitalization in the 2-months prior to randomization.
5. Completed PR program in the last 12 months.
6. Inability to complete 10 repetitions in the 1-minute sit-to-stand test or 5-second single-leg stance
7. Pregnancy
8. Inability to provide informed consent due to impaired decision-making capacity, as determined by the study's capacity assessment.

Where it's running

• Barzilai Medical Center
  Ashkelon, Israel Recruiting
• Tel Aviv Sourasky Medical Center
  Tel Aviv, Israel Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Enhanced COPD care for people being checked for lung cancer

  This project will test whether finding and treating COPD early in people being checked for possible lung cancer helps symptoms, lung function, and overall care.

  Recruiting Region of Southern Denmark · Vejle · NCT07543601

• How viral infections affect people with chronic lung disease

  This study will test if respiratory viruses trigger flare-ups and change immune responses in adults with COPD or bronchiectasis.

  Recruiting Imperial College London · London · NCT06625944

• Routine versus on-demand ECMO during lung transplant

  This trial tests whether using ECMO routinely during lung transplant or only when needed leads to fewer complications for people having a lung transplant.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Edmonton, Alberta and 3 other locations · NCT06615492

• Chronic Respiratory Disease Participant Engagement

  This study tests whether adults with long-term lung conditions can get comfortable with a clinical trials unit and research team before joining future trials.

  Recruiting Richmond Pharmacology Limited · London · NCT07924462

• High-Flow Nasal Cannula vs Noninvasive Ventilation in COPD with Hypercapnia

  This study tests whether a high-flow nasal cannula can better support gas exchange and comfort compared with noninvasive ventilation in COPD patients with mild-to-moderate elevated CO2.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07854210

• Sleep problems in PAH patients: how sleep breathing relates to PAH outcomes

  This study tests how sleep-disordered breathing and nocturnal oxygen changes relate to outcomes in adults with pulmonary arterial hypertension.

  Recruiting Chinese Pulmonary Vascular Disease Research Group · Beijing · NCT07852403

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.