Tail Fat Application for Knee Osteoarthritis Pain and Stiffness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled study investigates the effects of applying sheep tail fat, in addition to standard medical care, on knee pain, stiffness, and daily living activities in patients with gonarthrosis. Eligible adults with a knee osteoarthritis diagnosis and moderate pain will be randomized to receive the fat application plus standard treatment or standard treatment alone. The intervention leverages bioactive components found in sheep tail fat that may have anti-inflammatory and chondroprotective properties. Outcomes include changes in pain scores, stiffness, and functional measures over a defined follow-up period. The study is conducted at Bitlis State Hospital and Bitlis Tatvan State Hospital in Turkey, led by Inonu University.

Why it matters

Who can join: the full rules

\*\*Inclusion Criteria\*\*

* Patients diagnosed with gonarthrosis by a physician.
* Patients with a VAS score above 4.
* Individuals who have experienced pain related to knee osteoarthritis for at least the last 3 months.
* Participants aged 18 years and older.
* Individuals without an allergy to sheep tail fat or other animal products.
* Individuals who can communicate in Turkish and understand written and verbal instructions.
* Individuals who can apply the sheep tail fat according to the instructions.
* Individuals who agree to participate in the study.

\*\*Exclusion Criteria\*\*

* Individuals with severe physical disability or mental/psychological problems in the knee region.
* Individuals with intellectual or cognitive limitations.
* Individuals who have undergone knee surgery within the last year.
* Individuals with peripheral vascular disease.
* Individuals with infection, wound, cellulitis, or active skin disease in the knee region.
* Individuals who have experienced knee trauma or received an intra-articular steroid injection within the last six months.
* Individuals diagnosed with secondary arthritis or inflammatory joint disease.
* Pregnant or breastfeeding women.
* Individuals with active bleeding disorders.
* Individuals with asthma and individuals with liver or kidney failure.
* Individuals with connective tissue diseases (e.g., lupus, systemic sclerosis).
* Individuals who have experienced a serious infection within the last three months or are immunosuppressed.
* Individuals with neurological diseases affecting knee stability.

Where it's running

• Bitlis State Hospital
  Bitlis, Turkey (Türkiye) Recruiting
• Bitlis Tatvan State Hospital
  Bitlis, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Medet KORKMAZ
• Email: medet.korkmaz@inonu.edu.tr
• Phone: 05065027980

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.