Knee Osteoarthritis: See If Your Treatment Beliefs Help Your Physical Therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines whether pre-treatment expectations are linked to the outcomes of a conventional physical therapy program for knee osteoarthritis. Adults over 50 with radiographically confirmed KOA and stage 2–4 OA will participate in standard physical therapy, with researchers exploring how patients’ expectations relate to pain, function, and quality of life changes. The study aims to provide clinicians with insights on how patient mindset may affect treatment response. Data will come from clinical assessments and questionnaires during the therapy course and follow-up. Findings could help tailor pre-treatment conversations and shared decision-making in knee OA care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Agreeing to participate in the study
* Being over 50 years of age
* Having a clinically and radiographically confirmed diagnosis of knee osteoarthritis
* Having grade 2-3-4 knee osteoarthritis according to the Kellgren-Lawrence grading system
* Being literate

Exclusion Criteria:

* Previous knee surgery
* Conditions that prevent exercise (such as incurable malignancy, active systemic infection, non-union fracture)
* Presence of accompanying neurological disease affecting the lower extremity
* Severe cognitive impairment (neuropsychiatric disease or condition that will impede cooperation, such as psychosis, dementia)
* History of having received injections or other procedures to the knee joint or physical therapy within the last 6 months

Where it's running

• Gazi University
  Ankara, Yenimahalle, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Levent Karatas — Gazi University
• Study coordinator: Burak Tokac
• Email: buraktokac96@gmail.com
• Phone: +905313474837

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.