Surfactant delivery methods in preterm infants with RDS in Sweden

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects data on surfactant administration methods for preterm infants with RDS across Swedish neonatal units, using standard care as the setting. It compares approaches such as INSURE, LISA, SALSA, and traditional endotracheal administration, to observe associations with clinical outcomes. Data are gathered prospectively and linked to the Swedish Neonatal Quality Register for long-term follow-up, with the aim of informing future randomized trials. The analysis will explore real-world practice patterns, safety signals, and outcome trends across participating centers. The study emphasizes non-randomized, observational assessment rather than experimental intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient has received surfactant by any administration method
* Gestational age below 37 weeks'
* First surfactant treatment given before 48 hours of age
* Confirmed or suspected diagnosis of respiratory distress syndrome (RDS)

Exclusion Criteria:

• Not fulfilling above inclusion criteria

Where it's running

• Neonatal Intensive Care Unit, Sahlgrenska University Hostal
  Gothenburg, Sweden Recruiting

Study contacts

• Principal investigator: Anders Elfvin, Professor — Department of Neonatology, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden
• Study coordinator: Anders Elfvin, Professor
• Email: anders.elfvin@vgregion.se
• Phone: +46313438073

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.