Breathing patterns in preterm infants before and after extubation.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational pilot measures work of breathing in intubated premature infants before, during, and after routine spontaneous breathing trials and after extubation if performed. Soft elastic respiratory inductive plethysmography (RIP) bands placed around the chest and abdomen will record chest and abdominal motion and derived work-of-breathing indices. The study compares these RIP-derived indices to routine clinical measures and spontaneous breathing trial results to see whether RIP predicts extubation failure. Infants born at ≤32 weeks gestation undergoing extubation evaluation in the ChristianaCare NICU are eligible, with exclusions for conditions that affect RIP accuracy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* premature infants (born at ≤32 weeks gestation) who are intubated.
* medical team is evaluating the baby for extubation readiness

Exclusion Criteria:

* Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of RIP measurements will be excluded.

Where it's running

• ChristianaCare Health Services, Inc.
  Newark, Delaware, United States Recruiting

Study contacts

• Principal investigator: Kelley Z Kovatis, MD — Christiana Care Health Services, Inc
• Study coordinator: Kelley Z. Kovatis, MD
• Email: kelley.kovatis@christianacare.org
• Phone: 302-301-2410

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.