Video-guided vs direct laryngoscopy for less invasive surfactant delivery in extremely preterm infants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two visualization methods during less invasive surfactant administration in neonates born at or before 28 weeks gestation. The goal is to see if video laryngoscopy improves first-attempt success compared with direct laryngoscopy, and to describe potential benefits of each approach. Eligible infants are those resuscitated in the delivery room, on CPAP, and requiring surfactant within 36 hours of life. Exclusions include infants born after 28 weeks, with major congenital anomalies, those receiving comfort care, or those intubated before surfactant. The study is led by University of Texas Southwestern Medical Center at Parkland Hospital in Dallas, Texas.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infants born ≤28 weeks GA successfully resuscitated in the delivery room (DR) and maintained on CPAP • Need for surfactant in the first 36 hours of life based on clinical assessment and/or meeting threshold per unit protocol

Exclusion Criteria:

* Infants born ≥29 weeks GA or
* Infants with known congenital anomalies or
* Infants who are determined by the primary care team to receive comfort care only or
* Infants who are intubated at any time prior to surfactant administration

Where it's running

• Parkland Hospital
  Dallas, Texas, United States Recruiting

Study contacts

• Principal investigator: Chokshi, MD — UT Southwestern
• Study coordinator: Principal Investigator, MD
• Email: riti.chokshi@utsouthwestern.edu
• Phone: 214-648-3383

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.