Comparing video laryngoscopy and direct laryngoscopy for surfactant administration in newborns

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the effectiveness of video laryngoscopy versus direct laryngoscopy for the insertion of a thin endotracheal catheter in newborn infants requiring surfactant administration due to respiratory distress syndrome. The study will involve newborns who are experiencing breathing difficulties and require a thin catheter for surfactant delivery. By utilizing video laryngoscopy, which provides a magnified view of the airway, the study seeks to determine if this method improves the success rate of catheter insertion compared to the traditional direct laryngoscopy approach. Data will be collected from multiple clinical sites to assess outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* newborn infants of any sex who are are having a thin catheter inserted into their trachea for the purpose of surfactant administration

Exclusion Criteria:

* no parental consent provided to share their data

Where it's running

• Clinical Hospital Centre
  Rijeka, Croatia Recruiting
• Clinical Hospital "Holy Spirit"
  Zagreb, Croatia Recruiting
• University Hospital Brno
  Brno, Czechia Recruiting
• General University Hospital
  Prague, Czechia Recruiting
• Institute for Mother and Child Care
  Prague, Czechia Recruiting
• Aristotle University of Thessaloniki
  Thessaloniki, Greece Recruiting

Study contacts

• Principal investigator: Colm P.F. O'Donnell, MB PhD — National Maternity Hospital, Dublin, Ireland
• Study coordinator: Colm P.F. O'Donnell, MB PhD
• Email: codonnell@nmh.ie
• Phone: +35316373100

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Surfactant delivery methods in preterm infants with RDS in Sweden

  This study tests different ways of giving surfactant to preterm babies with respiratory distress to see which method works best when care is routine.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT07550218

• Comparing calfactant and poractant alfa delivered by a less invasive catheter to treat respiratory distress in very preterm infants

  This will see if poractant alfa or calfactant given through a thin catheter (LISA) helps preterm infants under 30 weeks with respiratory distress who are breathing on noninvasive support.

  Recruiting at 5 sites Phase 4 Uludag University · Bursa and 4 other locations · NCT07350018

• SalSA vs LISA: Surfactant Delivery in Preterm Infants

  This study tests whether giving surfactant through SALSA (a supraglottic airway) is safer and more effective than the LISA thin-catheter method in babies born at 29-36 weeks who need help breathing.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07030270

• How Different Levels of CPAP Deliver Oxygen to Preterm Babies

  This study tests how much oxygen actually reaches preterm infants when they receive nasal CPAP at different air pressures.

  Recruiting University of Arkansas · Little Rock, Arkansas and 1 other locations · NCT07674953

• Hyperangulated vs. Macintosh blades for obstetric intubation

  This study tests whether a hyperangulated blade or a Macintosh-style blade helps obstetric patients get an endotracheal tube placement more safely during cesarean deliveries under general anesthesia.

  Recruiting Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Toronto, Ontario · NCT07667010

• Breathing patterns in preterm infants before and after extubation.

  This will try to see if measuring work of breathing with soft chest and abdominal bands can predict which intubated premature infants (≤32 weeks) will tolerate removal of their breathing tube.

  Recruiting Christiana Care Health Services · Newark, Delaware · NCT07542301

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.