Condition

Respiratory Distress Syndrome in Premature Infant clinical trials and research

• 10Clinical trials
• 12Countries

Newest Respiratory Distress Syndrome in Premature Infant clinical trials

All recruiting trials (10)

• Surfactant delivery methods in preterm infants with RDS in Sweden

  This study tests different ways of giving surfactant to preterm babies with respiratory distress to see which method works best when care is routine.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT07550218

• Lung ultrasound score to guide surfactant timing in preterm newborns

  This study tests whether using a lung ultrasound score can speed up diagnosing severe RDS and getting surfactant to moderately and late-preterm babies in the NICU.

  Recruiting Hackensack Meridian Health · Hackensack, New Jersey · NCT07442669

• Predicting which newborns in a lower-level NICU will need extended breathing support

  This project will test whether analyzing a newborn's stomach fluid right after birth can help predict which babies born at 32+ weeks and attended by the neonatal resuscitation team will need breathing support for more than six hours.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07344714

• Optimising breathing support at extubation for very preterm infants

  This trial will try starting nasal CPAP before removing the breathing tube versus starting it after extubation to see if that reduces oxygen drops in very preterm infants.

  Recruiting at 3 sites Murdoch Childrens Research Institute · Melbourne, Victoria and 2 other locations · NCT07251790

• Surfactant given through a laryngeal mask for preterm babies with RDS in Vietnam

  For preterm babies under 34 weeks with respiratory distress, the team will try giving surfactant through a soft throat mask (SALSA) instead of an endotracheal tube (INSURE) to see if it reduces the need for invasive breathing support.

  Recruiting Karolinska Institutet · Hanoi · NCT07098910

• Giving surfactant to premature infants using a thin catheter at birth

  This study is testing if giving a special lung treatment to very premature babies right after birth using a thin tube can help them breathe better and need less breathing support in their first few days of life.

  Recruiting University College Dublin · Dublin, None Selected · NCT06557551

• Evaluating a new surfactant treatment for respiratory distress in preterm infants in Africa

  This study is testing a new way to give surfactant treatment to preterm infants with breathing problems in Africa to see if it helps them do better than the usual care.

  Recruiting at 2 sites Phase 4 Indiana University · Bangui and 7 other locations · NCT06554522

• Comparing breathing support methods for preterm infants

  This study is testing which breathing support method, CPAP or NIPPV, works better for very low birth weight preterm infants by comparing how their diaphragm functions while using each method.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06295484

• Personalized surfactant delivery using lung mechanics in preterm infants

  This study tests whether giving surfactant guided by lung mechanics measurements helps preterm babies need less time on respiratory support.

  Recruiting Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Milan · NCT05791331

• Comparing non-pharmacological and analgesic approaches for surfactant treatment in premature infants

  This study is testing if using a non-drug approach during surfactant treatment helps premature infants breathe better compared to using pain relief medication.

  Recruiting at 2 sites Copenhagen University Hospital, Rigshospitalet · Aalborg and 3 other locations · NCT05609877

Related topics

Quick answers

How many Respiratory Distress Syndrome in Premature Infant clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (2 trials), Sweden (1 trial), Vietnam (1 trial), Canada (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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