SPSIP vs RISS Block for pain relief after volume-preserving VATS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized study compares two ultrasound-guided fascial plane blocks—SPSIP and RISS—to manage postoperative pain in adults undergoing volume-preserving VATS. Eighty-four participants are assigned 1:1 to receive either SPSIP or RISS blocks. The primary outcome is the rate of somatic chest drain site pain at 2 hours after surgery, with secondary outcomes including overall pain scores, opioid use, quality of recovery, diaphragmatic movement, lung function, need for rescue analgesia, PONV, and block-related complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients scheduled for elective biportal video-assisted thoracoscopic surgery (VATS) with lung parenchyma-preserving thoracic procedures under general anesthesia
* American Society of Anesthesiologists (ASA) physical status I-III
* Age between 18 and 75 years
* Provision of written informed consent

Exclusion Criteria:

* Use of anticoagulant or antiplatelet therapy
* Bleeding diathesis
* Known allergy to local anesthetics
* Infection at the planned block site
* Severe chronic pulmonary disease or advanced respiratory failure (e.g., severe COPD or restrictive lung disease)
* Cognitive impairment preventing reliable NRS assessment
* Pregnancy or lactation
* Chronic opioid use (regular use for ≥3 months)
* Severe hepatic or renal failure
* Refusal to participate
* Technical failure or unsuccessful regional block
* Conversion to open thoracotomy during surgery

Where it's running

• Bursa City Hospital
  Bursa, Nilüfer, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Yusuf Alan
• Email: dryusufalan@gmail.com
• Phone: +905396210977

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.