Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Ultrasound-Guided Rhomboid-Intercostal Block vs Thoracic Paravertebral Block for Pain Control After VATS

Official title: Comparison of the Ultrasound-Guided Rhomboid-Intercostal Block (RIB) Versus Thoracic Paravertebral Block (PVB) for Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery (VATS): A Double-Blind Randomized Controlled Trial

Run by Blue Cross of Thessaloniki · NCT07465887 · Data updated 2026-11-12

This study tests whether the rhomboid-intercostal block (RIB) or the thoracic paravertebral block (PVB) provides better pain relief after a 3-port VATS chest surgery in adults.

More Postoperative Pain trials

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment60 (estimated)
SponsorBlue Cross of Thessaloniki
Academic / other
Locations1 site (Thessaloniki)
StatusRecruiting
StartedMarch 9, 2026
Main results expectedMarch 2027
Study endsMarch 2027
Registry record updatedOctober 8, 2026
Trial IDNCT07465887 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-85 undergoing elective 3-port unilateral VATS, with ASA I-III, and no contraindications to regional anesthesia.

Probably not a fit

Patients with contraindications to local anesthetics, infection at the injection site, coagulation disorders, or obesity (BMI > 35) may not benefit from the interventions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, double-blind, randomized trial comparing two ultrasound-guided regional anesthesia techniques for post-operative analgesia in adults undergoing elective 3-port VATS. Participants are randomized 1:1 to receive either RIB or PVB at the T5 level with 30 ml of 0.375% ropivacaine after induction of general anesthesia. Pain will be assessed at rest and with deep breathing during the first 24 hours, and rescue analgesia protocols are in place for uncontrolled pain. Safety monitoring includes checks for hypotension, respiratory depression, and nausea, along with standard post-operative observations. The study aims to determine which block provides superior analgesia with a standardized post-operative regimen.

Why it matters

Potential benefit: If successful, this trial could identify a more effective regional anesthesia technique to reduce post-operative pain after VATS.

How similar studies have gone: Past studies have explored regional blocks for thoracic surgery, with mixed results; this trial adds a direct comparison under ultrasound guidance for VATS analgesia.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (18-85 years old),
* ASA physical status I-III
* scheduled for elective 3-port unilateral VATS.

Exclusion Criteria:

* Allergy to local anesthetics
* infection at the injection site
* coagulation disorders
* severe neurological disorder
* obesity (BMI \> 35)
* opioid addiction
* conversion to open thoracotomy, admission to ICU.
* renal disease, high serum Creatinine levels

Where it's running

  • Blue Cross Thessaloniki
    Thessaloniki, Greece
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.