Speech motor learning and retention in adults using brain stimulation and fMRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study uses transcranial magnetic stimulation and functional MRI to identify brain regions involved in learning and retaining new speech movements. Participants will undergo speech adaptation tasks with Harvard Sentences, while resting-state and task-based imaging track neural activity. The protocol includes sessions to test retention 24 hours after learning, with assessments of brain excitability. The aim is to map how sensory and motor brain areas contribute to motor memory for speech.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Fluent English speakers
* Right-handed
* Normal hearing
* No speech disorder or reading disability

Exclusion Criteria:

* Cardiac pacemaker
* Aneurysm clip
* Heart or Vascular clip
* Prosthetic valve
* Metal implants
* Metal in brain, skull, or spinal cord
* Implanted neurostimulator
* Medication infusion device
* Cochlear implant or tinnitus (ringing in ears)
* Personal and/or family history of epilepsy or other neurological disorders or history of head concussion
* Psychoactive medications
* Pregnancy

Where it's running

• Yale Child Study Center
  New Haven, Connecticut, United States Recruiting

Study contacts

• Principal investigator: David Ostry — Yale University
• Study coordinator: Michael Stern
• Email: michael.stern@yale.edu
• Phone: 2038656163

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.