Socket preservation after tooth extraction with autogenous dentin

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized trial compares four socket preservation methods after non-molar tooth extraction: spontaneous healing with a stitch, collagen sponge alone, collagen sponge with a tricalcium phosphate graft, and autogenous dentin with collagen sponge. The main outcome is the change in ridge width and height measured by CBCT at baseline and six months, with analyses at multiple depths (1, 3, and 5 mm). Participants are adults aged 18-70 without active periodontitis, undergoing extraction for standard care, and without conditions that could affect healing. Subgroup analyses will explore how soft tissue factors influence outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18-70 years
* no active periodontitis
* signed informed consent with participation in the study
* need for extraction of teeth other than third molars
* patients requesting only standard/reimbursed care

Exclusion Criteria:

* drug or alcohol abuse
* ongoing chemotherapy
* ongoing radiotherapy
* pregnancy
* ongoing treatment of osteoporosis or other biological treatment with MRONJ risk
* low compliance
* patients asking for premium care

Where it's running

• University Hospital Ostrava
  Ostrava, Czechia Recruiting

Study contacts

• Study coordinator: Petr Jalůvka, MDDr.
• Email: petr.jaluvka@osu.cz
• Phone: +420 596 623 518

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of four post-extraction socket approaches on preserving the ridge after tooth removal

  This study tests four ways to care for an extraction socket to see which best preserves the jawbone and gum after tooth removal for future implants.

  Recruiting Universidad del Desarrollo · Santiago, Santiago Metropolitan · NCT07812883

• Bone-preserving grafting with Biphasic Calcium Phosphate after tooth extraction

  This trial tests whether Neobone biphasic calcium phosphate grafts help preserve bone volume in tooth extraction sites compared with natural healing.

  Recruiting Early Phase 1 Egas Moniz - Cooperativa de Ensino Superior, CRL · Caparica, Monte Da Caparica · NCT07638358

• Beta-Tricalcium Phosphate for preserving the ridge after tooth extraction

  This early-phase trial tests whether beta-tricalcium phosphate helps preserve bone volume after tooth extraction compared with natural healing.

  Recruiting Early Phase 1 Egas Moniz - Cooperativa de Ensino Superior, CRL · Caparica, Monte Da Caparica · NCT07638319

• Nd:YAG laser to improve gum healing after tooth extraction and ridge preservation

  This test tries whether multiple Nd:YAG low-level laser sessions after tooth extraction and alveolar ridge preservation help adults heal faster and have less pain.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07095556

• Jaw ridge changes after tooth removal and ridge preservation

  We will see if a socket that widens right after a tooth is removed or stays the same changes ridge width and height four months later in adults having a single extraction with bone graft and a resorbable membrane.

  Recruiting Marquette University · Milwaukee, Wisconsin · NCT06624982

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.