Bone-preserving grafting with Biphasic Calcium Phosphate after tooth extraction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized early-phase study compares using Neobone biphasic calcium phosphate to allow natural healing after tooth extraction. Participants will have CBCT and intra-oral scans at baseline and after six months to measure changes in ridge width, height, and bone density. Outcomes focus on whether the graft helps maintain/better preserve alveolar ridge volume for future implant sites. The study includes adults requiring extraction and excludes those with active infection, poor oral hygiene, uncontrolled diabetes, heavy smoking, or other risk factors for implant surgery. Data will inform whether this graft material improves bone preservation over standard healing.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years or older
* Acceptance of informed consent
* Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion Criteria:

* Presence of active infection or severe inflammation in the intervention zone
* Relevant medical history that contraindicates implant surgery
* Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation
* Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
* Uncontrolled and /or untreated periodontal disease
* Heavy smokers (more than 10 cigarettes per day)
* Immunosuppression

Where it's running

• Clinica Dentária Egas Moniz
  Caparica, Monte Da Caparica, Portugal Recruiting

Study contacts

• Study coordinator: Angel Lobito, Masters' in Dentistry
• Email: alobito@egasmoniz.edu.pt
• Phone: 00351924347050

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of four post-extraction socket approaches on preserving the ridge after tooth removal

  This study tests four ways to care for an extraction socket to see which best preserves the jawbone and gum after tooth removal for future implants.

  Recruiting Universidad del Desarrollo · Santiago, Santiago Metropolitan · NCT07812883

• Beta-Tricalcium Phosphate for preserving the ridge after tooth extraction

  This early-phase trial tests whether beta-tricalcium phosphate helps preserve bone volume after tooth extraction compared with natural healing.

  Recruiting Early Phase 1 Egas Moniz - Cooperativa de Ensino Superior, CRL · Caparica, Monte Da Caparica · NCT07638319

• Socket preservation after tooth extraction with autogenous dentin

  This study tests four ways to preserve the tooth socket after extraction to see which best maintains bone size for future implants.

  Recruiting University of Ostrava · Ostrava · NCT07608289

• Alveolar ridge preservation and whether it lowers the need for sinus floor elevation after upper back tooth extraction

  This project tries to see if filling the socket after removing upper back teeth reduces the chance you'll need a sinus lift before getting a dental implant.

  Recruiting Saint-Joseph University · Beirut, Beirut · NCT07526129

• Demineralized versus mineralized dentin grafts to preserve the upper back tooth ridge

  We will test whether demineralized or mineralized donor dentin grafts better preserve bone after removing a single upper back tooth in healthy adults.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh · NCT07242313

• Nd:YAG laser to improve gum healing after tooth extraction and ridge preservation

  This test tries whether multiple Nd:YAG low-level laser sessions after tooth extraction and alveolar ridge preservation help adults heal faster and have less pain.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07095556

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.