See if VExUS ultrasound can guide fluid decisions in ICU patients with venous congestion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial evaluates the use of multi-site venous ultrasound to calculate the VExUS score in adult ICU patients with venous congestion. The goal is to see if the VExUS-guided assessment can help avoid excessive fluid administration and related complications in critical illness, including ARDS. The study uses ultrasound of the inferior vena cava, portal vein, suprahepatic vein, renal vein, femoral vein, and popliteal vein to derive the VExUS score and inform fluid management. Enrollment is limited to adults admitted to the medical ICU at Besançin Teaching Hospital who consent and meet eligibility criteria. The investigation aims to correlate ultrasound findings with clinical outcomes and congestion-related risks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients admitted to medical intensive care at Besançon Teaching Hospital for any reason.
* Aged over 18.
* Affiliated with a French social security scheme or beneficiary of such a scheme.
* No objection to participating in the study.

Non-inclusion criteria :

* Minors
* Pregnant women and breastfeeding mothers
* Persons deprived of their liberty by judicial or administrative decision; persons undergoing compulsory psychiatric treatment; persons admitted to a health or social care institution for purposes other than research
* Adults subject to legal protection measures or unable to give their consent
* Subjects who are excluded from another study or listed in the 'national volunteer registry'.

Exclusion Criteria:

\- Portal vein, suprahepatic or femoral vein thrombosis at the time of ultrasound examination.

Where it's running

• Centre Hospitalier Universitaire Jean MINJOZ
  Besançon, France Recruiting

Study contacts

• Study coordinator: Hadrien WINISZEWSKI, MCU-PH
• Email: hwiniszewski@chu-besancon.fr
• Phone: 0033381668127

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Right ventricular–arterial coupling during fluid loading in ICU patients

  This study tests how the right ventricle handles fluid changes in critically ill adults to see how it affects blood flow and congestion.

  Recruiting CHU de Reims · Reims · NCT07537621

• How giving fluids changes tiny blood flow in critically ill patients with venous congestion.

  This project will see if giving a fluid bolus makes tiny blood flow worse in ICU patients who have venous congestion compared with similar patients without congestion.

  Recruiting Università Politecnica delle Marche · Ancona, Italy · NCT07499401

• Venous congestion and delirium after heart surgery

  This project will see if venous congestion during and after elective heart surgery is linked to a higher risk of postoperative delirium in adults who can complete cognitive testing.

  Recruiting Yangzhou University · Yangzhou, Jiangsu · NCT07285187

• Venous congestion and microcirculation after elective cardiac surgery

  This project will try to see if bedside ultrasound signs of venous congestion (VEXUS score and femoral vein Doppler) are linked with microcirculatory problems in adults during their ICU stay after elective or urgent cardiac surgery.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT07052461

• Investigating fluid responsiveness and venous congestion in critically ill patients during volume expansion

  This study is testing how well critically ill patients respond to extra fluids and if they have too much fluid in their veins during treatment in the ICU.

  Recruiting at 3 sites Bicetre Hospital · Guangzhou, Guangdong and 2 other locations · NCT06772038

• Guided fluid removal using VeXUS score for patients with acute kidney injury after heart surgery

  This study is testing if using the VeXUS score to manage fluid levels can help patients with acute kidney injury after heart surgery recover better than standard care.

  Recruiting Hospices Civils de Lyon · Bron, Bron and 1 other locations · NCT06251713

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.