How giving fluids changes tiny blood flow in critically ill patients with venous congestion.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling critically ill patients in the intensive care unit who have invasive or minimally invasive hemodynamic monitoring. Patients who receive a clinician-ordered fluid challenge will have microcirculatory measurements taken before and after the fluid is given. Investigators will compare microcirculatory changes between patients with clinical signs of venous congestion and those without. The aim is to determine whether fluid administration worsens microvascular perfusion in patients with venous congestion.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Critically ill patients admitted to the intensive care unit
* Invasive or minimally invasive hemodynamic monitoring

Exclusion Criteria:

* Suspected or confirmed pregnancy
* Inability to access the oral cavity (e.g., facial trauma, oral bleeding)

Where it's running

• AOU delle Marche
  Ancona, Italy, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.