See if the ED admission decisions are appropriate
Official title: Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Hospitalizations: Validation of an Algorithm Based on Computerized Hospital Databases
Run by Mario Negri Institute for Pharmacological Research · NCT06846879 · Data updated 2026-11-12
This study tests whether the decision to admit patients from the emergency department is appropriate for adults who come in with symptoms like chest pain, shortness of breath, fainting, or abdominal pain.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 240000 (estimated) |
| Sponsor | Mario Negri Institute for Pharmacological Research Academic / other |
| Locations | 7 sites (Alessandria and 6 other locations) |
| Status | Recruiting |
| Started | January 5, 2026 |
| Main results expected | September 2026 |
| Study ends | June 2027 |
| Registry record updated | May 19, 2026 |
| Trial ID | NCT06846879 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who arrived at participating EDs between January 1, 2023 and December 31, 2024 with symptoms such as dyspnea, chest pain, transient loss of consciousness, or abdominal pain.
✕Probably not a fit
Patients whose presentations do not lead to admission decisions may not benefit directly from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study uses ED records and available databases to develop and validate a method for judging the clinical appropriateness of ED admission decisions. It focuses on adults presenting with non-specific symptoms in pulmonary, cardiovascular, or abdominal domains. Analysis will be restricted to data from 2023-2024 to ensure feasibility. The goal is to create a sustainable approach to measure whether hospital admissions from the ED are warranted given the patient’s presentation.
Why it matters
Potential benefit: If successful, the method could improve decision-making in the ED and reduce unnecessary hospitalizations.
How similar studies have gone: Prior work in ED analytics has shown promise in evaluating admission appropriateness, but methods vary and broad validation is ongoing.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients aged 18 years and over who arrived at participating centres between 1 January 2023 and 31 December 2024. Exclusion Criteria: All patients under 18 years of age arriving at participating centers between January 1, 2023 and December 31, 2024 and all patients arriving at participating centers outside the time frame January 1, 2023 - December 31, 2024.
Where it's running
-
AOU SS. Antonio e Biagio e Cesare Arrigo
Alessandria, Italy Recruiting -
A.O. S. Croce e Carle
Cuneo, Italy Not yet recruiting -
Ospedale Maggiore della Carità
Novara, Italy Not yet recruiting -
Ospedale S. Giacomo
Novi Ligure, Italy Not yet recruiting -
Ospedale San Luigi Gonzaga
Orbassano, Italy Not yet recruiting -
Ospedale degli Infermi
Rivoli, Italy Not yet recruiting
Show 1 more location
-
Ospedale San Giovanni Bosco
Torino, Italy Not yet recruiting
Study contacts
- Study coordinator: Guido Bertolini, MD
- Email: guido.bertolini@marionegri.it
- Phone: +39 035 4535389
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Understanding parental well-being after childbirth in Switzerland
This study looks at how new parents in Switzerland feel and cope during the first year after having a baby to see how postnatal care can be improved.
-
Assessing lymph node removal quality during minimally invasive gastric cancer surgery
This study is testing a new scoring system to see if it can help doctors better assess lymph node removal during minimally invasive surgery for stomach cancer and improve patient outcomes.
-
Universal Test and Connect for HIV services in Cape Town emergency departments
This project tests whether offering universal HIV testing and connection-to-care in two Cape Town emergency departments can find people with HIV or at high risk and link them to treatment or PrEP.
-
Using D-dimer to improve patient discharge in emergency departments
This study tests if checking D-dimer levels can help doctors quickly identify low-risk patients in emergency departments who don't need to stay in the hospital.
-
Examining emergency department management for out-of-hospital cardiac arrest patients
This study looks at how different treatments in the emergency department can help improve survival and brain function for adults who have had a cardiac arrest outside the hospital.
-
Evaluating targeted therapy effectiveness in advanced lung cancer using RecistTM criteria
This study is testing if a new way to measure how well targeted therapy works can help people with advanced lung cancer who have specific gene changes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.