Screening and evaluation for substance use disorders at NIDA
Official title: Screening, Evaluation, and Assessment (SEA) Protocol at the NIDA IRP
Run by National Institutes of Health Clinical Center (CC) · NCT06552741 · Data updated 2026-11-12
This study is trying to see if people with and without substance use disorders can join future research at NIDA to help understand drug use and improve treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | September 4, 2024 |
| Main results expected | January 1, 2045 |
| Study ends | January 1, 2047 |
| Registry record updated | August 24, 2026 |
| Trial ID | NCT06552741 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 years and older, whether they currently use substances, have previously used them, or have never used them.
✕Probably not a fit
Patients who lack the capacity to consent to research participation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This protocol involves screening individuals with and without substance use disorders (SUD) to assess their eligibility for participation in ongoing clinical research at the National Institute on Drug Abuse (NIDA). Participants will undergo a comprehensive evaluation process that may last up to 8 hours, during which data will be collected to understand drug use behaviors and develop potential treatments for SUD. The study aims to create a registry of participants interested in future research opportunities and to enhance the understanding of the effects of SUD on various organ systems.
Why it matters
Potential benefit: If successful, this study could lead to improved treatments for individuals struggling with substance use disorders.
How similar studies have gone: Other studies have shown success in using similar screening and evaluation approaches to enhance understanding and treatment of substance use disorders.
Who can join: the full rules
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: This protocol is seeking individuals with current or past SUDs and/or AUD, as well as those who have never had an SUD or AUD. These individuals also may or may not be in treatment for their AUD/SUDs. To be eligible to participate in this study, an individual must meet the following criteria: * Age 18-99 years old. * Proficient ability to read, write, and understand English. * Stated willingness to comply with all screening procedures and availability for the duration of the screening period * Ability of subject to understand and the willingness to sign a written informed consent document. EXCLUSION CRITERIA: Individuals who lack capacity to consent to research participation to this protocol as determined by the Evaluation to Sign Consent (ESC).
Where it's running
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National Institute on Drug Abuse
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Lorenzo Leggio, M.D. — National Institute on Drug Abuse (NIDA)
- Study coordinator: Shannon M Pfistner
- Email: pfistners@nida.nih.gov
- Phone: (800) 535-8254
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.