Screening and evaluation for substance use disorders at NIDA

Screening, Evaluation, and Assessment (SEA) Protocol at the NIDA IRP

Observational National Institutes of Health Clinical Center (CC) · NCT06552741

This study is trying to see if people with and without substance use disorders can join future research at NIDA to help understand drug use and improve treatments.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) NIH
Locations1 site (Baltimore, Maryland)
Trial IDNCT06552741 on ClinicalTrials.gov

What this trial studies

This protocol involves screening individuals with and without substance use disorders (SUD) to assess their eligibility for participation in ongoing clinical research at the National Institute on Drug Abuse (NIDA). Participants will undergo a comprehensive evaluation process that may last up to 8 hours, during which data will be collected to understand drug use behaviors and develop potential treatments for SUD. The study aims to create a registry of participants interested in future research opportunities and to enhance the understanding of the effects of SUD on various organ systems.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 18 years and older, whether they currently use substances, have previously used them, or have never used them.

Not a fit: Patients who lack the capacity to consent to research participation will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatments for individuals struggling with substance use disorders.

How similar studies have performed: Other studies have shown success in using similar screening and evaluation approaches to enhance understanding and treatment of substance use disorders.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:

This protocol is seeking individuals with current or past SUDs and/or AUD, as well as those who have never had an SUD or AUD. These individuals also may or may not be in treatment for their AUD/SUDs.

To be eligible to participate in this study, an individual must meet the following criteria:

* Age 18-99 years old.
* Proficient ability to read, write, and understand English.
* Stated willingness to comply with all screening procedures and availability for the duration of the screening period
* Ability of subject to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA:

Individuals who lack capacity to consent to research participation to this protocol as determined by the Evaluation to Sign Consent (ESC).

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Substance Use DisorderAlcohol Use DisorderAlcoholDrugSmokingSubstanceOpioidNicotine
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.