Salivary biomarker panel to predict periodontal health over 2 years

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a longitudinal, observational follow-up study at the University Complutense de Madrid. Adults previously in a cross-sectional study will be re-evaluated at 1 and 2 years to see if salivary biomarkers correlate with changes in periodontal health. Participants will be categorized by the 2018 periodontal disease classifications and receive comprehensive medical measurements at each visit. No intervention will be given; the study relies on biomarker profiling and clinical follow-up to identify predictive patterns. The aim is to determine if saliva tests can help forecast periodontal status over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants from the cohort involved in the previous cross-sectional study (code 23/481-E).
* Adults (≥ 18-year-old)
* Being able to sign an informed consent form
* Willing to participate in this observational investigation
* Diagnosed as periodontally healthy, gingivitis, treated periodontitis patient (stable / unstable), periodontitis stages I \& II, or periodontitis stages III and IV (Papapanou et al. 2023) in the previous cross-sectional study (code 23/481-E)

Exclusion Criteria:

* Patients fitting to all the above inclusion criteria will be excluded from the study if unable to attend to the study-related procedures.

Where it's running

• Faculty of Dentistry, University Complutense of Madrid (UCM)
  Madrid, Spain Recruiting
• Faculty of Dentistry, University Complutense of Madrid (UCM)
  Madrid, Spain Recruiting

Study contacts

• Study coordinator: Elena Figuero, Prof.
• Email: elfiguer@ucm.es
• Phone: +34 913942186

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.