Daily peanut consumption for improving health in prediabetes
Impact of Peanuts on Cardiometabolic, Cognitive, and Intestinal Health in Prediabetes Among Racially Diverse Populations
This study is testing whether eating peanut butter every day can help people with prediabetes improve their health, including blood sugar levels and brain function.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 20 Years to 59 Years |
| Sex | All |
| Sponsor | Georgia State University Academic / other |
| Locations | 1 site (Atlanta, Georgia) |
| Trial ID | NCT06867198 on ClinicalTrials.gov |
What this trial studies
This 13-month randomized crossover study aims to evaluate the effects of daily peanut and peanut product consumption on cardiometabolic, cognitive, and intestinal health in a diverse population with prediabetes. The study will involve participants consuming 43 grams of peanut butter daily to assess improvements in health markers associated with prediabetes, including glucose levels and cognitive function. The research addresses the significant public health issue of prediabetes and its complications, particularly in underrepresented populations. By focusing on dietary modifications, the study seeks to provide evidence for the role of plant-based foods in managing prediabetes and preventing type 2 diabetes.
Who should consider this trial
Good fit: Ideal candidates for this study are men and women aged 20-59 who have been diagnosed with prediabetes.
Not a fit: Patients with allergies to peanuts or those with active serious health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a dietary intervention that significantly improves health outcomes for individuals with prediabetes.
How similar studies have performed: While emerging evidence suggests benefits of peanuts for health, this study is among the first to comprehensively evaluate their effects specifically in prediabetes populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * men and women * 20-59 years of age * BMI: 24.5 - 35.5 kg/m\^2 * Prediabetes (fasting blood glucose levels 100-125 mg/dL and/or HbA1c between 5.7-6.4%) * Ability to give consent Exclusion Criteria: * Allergies to peanuts and peanut products * Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs * Active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological diseases or severe head injury * Smoking * Consumes greater than 2 alcoholic beverages per day * Consumes antioxidant, probiotic, and prebiotic supplements * Pregnant or Lactating * Actively participating in a weight loss program MRI Exclusion Criteria: * Certain neurological disorders (e.g., uncontrolled seizure disorders) * Braces on their teeth, a cardiac pacemaker; hearing aid; other metal in the body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects
Where this trial is running
Atlanta, Georgia
- Georgia State University — Atlanta, Georgia, United States (Recruiting)
Study contacts
- Principal investigator: Rafaela G Feresin, PhD — Georgia State University
- Study coordinator: Rafaela G Feresin, PhD
- Email: peanuts@gsu.edu
- Phone: 404-413-1233
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.