Daily peanut consumption for improving health in prediabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This 13-month randomized crossover study aims to evaluate the effects of daily peanut and peanut product consumption on cardiometabolic, cognitive, and intestinal health in a diverse population with prediabetes. The study will involve participants consuming 43 grams of peanut butter daily to assess improvements in health markers associated with prediabetes, including glucose levels and cognitive function. The research addresses the significant public health issue of prediabetes and its complications, particularly in underrepresented populations. By focusing on dietary modifications, the study seeks to provide evidence for the role of plant-based foods in managing prediabetes and preventing type 2 diabetes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* men and women
* 20-59 years of age
* BMI: 24.5 - 35.5 kg/m\^2
* Prediabetes (fasting blood glucose levels 100-125 mg/dL and/or HbA1c between 5.7-6.4%)
* Ability to give consent

Exclusion Criteria:

* Allergies to peanuts and peanut products
* Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs
* Active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological diseases or severe head injury
* Smoking
* Consumes greater than 2 alcoholic beverages per day
* Consumes antioxidant, probiotic, and prebiotic supplements
* Pregnant or Lactating
* Actively participating in a weight loss program

MRI Exclusion Criteria:

* Certain neurological disorders (e.g., uncontrolled seizure disorders)
* Braces on their teeth, a cardiac pacemaker; hearing aid; other metal in the body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects

Where it's running

• Georgia State University
  Atlanta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Rafaela G Feresin, PhD — Georgia State University
• Study coordinator: Rafaela G Feresin, PhD
• Email: peanuts@gsu.edu
• Phone: 404-413-1233

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.