Family-based diabetes prevention for parents and kids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study assigns a 12-week, in-person family-based lifestyle intervention to parents with prediabetes or diabetes risk factors and their children. Primary outcome is weight loss in parents, with additional measures of weight, blood pressure, waist size, and lifestyle behaviors collected at baseline, after the program, and at a 3-month follow-up. Data are gathered via REDCap surveys and clinical assessments, including weekly parental weight checks and standard physical measurements. Participants attend 12 weekly sessions at a single site in Atlanta, GA, supported by Morehouse School of Medicine and NHLBI collaboration. The study aims to see if the program can promote sustainable healthy behaviors and family engagement to reduce type 2 diabetes risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Parent/guardian must identify as African American or Hispanic
* Parent/guardian must be 18+ years residing in the same household as the child (i.e., biological or have legal guardianship for child)
* Parent/guardian must have prediabetes (HbA1c level 5.7-6.4%) or be at risk of developing Type 2 diabetes using CDC's Pre-Diabetes Risk Test
* Participant is willing to commit to participation in a 12-week, in-person, intervention study
* No plans to move over the next 9-months
* Parent/guardian should be ambulatory and able to participate in physical activity
* Children must be between the ages of 12-17 years old
* Child should be ambulatory and able to participate in physical activity

Exclusion Criteria:

* Severe psychological disorders that may prevent/interfere with study -participation
* Physical impairments that may prevent participation in moderate intensity physical activity
* Previous diagnosis of diabetes
* History of congestive heart failure
* Renal failure
* Recent (\<12 months) cardiovascular events such as myocardial infarction (heart attack) or stroke
* Taking medications that may affect endpoint analyses
* Have co-morbid contraindications to physical activity or dietary changes
* Currently pregnant or planning to become pregnant in the next year
* Family lives outside of Georgia

Where it's running

• Morehouse School of Medicine
  Atlanta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Rakale C Quarells, PhD — Morehouse School of Medicine
• Study coordinator: Katrina M Brantley, DrPH
• Email: kbrantley@msm.edu
• Phone: 470-670-7840

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Lifestyle Metabotype Study B: Understanding Personalized Glucose Responses

  This study tests how lifestyle, metabolism, and brain energy use relate to each person’s blood sugar response after meals, across people with and without prediabetes or type 2 diabetes.

  Recruiting at 2 sites German Institute of Human Nutrition · Berlin and 1 other locations · NCT07888257

• Lifestyle Metabotype Study: How Daily Habits Shape Blood Sugar

  This observational study tests whether personal lifestyle and biological factors can predict how a person’s blood sugar responds after meals.

  Recruiting German Institute of Human Nutrition · Potsdam, Potsdam-Rehbrücke · NCT07868601

• Hourly stair-climbing snacks to improve blood sugar and heart health in adults with prediabetes

  This study tests whether short stair-climbing bursts every hour can improve blood sugar and vascular health in adults with prediabetes.

  Recruiting St. Louis University · St Louis, Missouri · NCT07847684

• Smart probiotic and nutraceutical approach for cardiometabolic health in older adults

  This trial tests whether a probiotic-containing nutraceutical strategy can improve metabolic health and blood pressure in adults over 65 with prediabetes or cardiovascular disease.

  Recruiting Azienda Ospedaliero Universitaria Maggiore della Carita · Novara · NCT07817290

• Cardiorespiratory and muscular fitness in children with obesity and autism

  This study tests whether cardiorespiratory fitness and handgrip strength differ between children with obesity who have autism and those who do not, and how these fitness measures relate to body size, composition, and cardiometabolic health.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07804680

• Health for Hungary: Long-term blood and health data collection to study aging and disease onset

  This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.

  Recruiting at 21 sites Center for Molecular Fingerprinting Research Nonprofit LLC · Balatonfüred and 32 other locations · NCT07743021

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.