Right heart dysfunction in acute pulmonary embolism: can echocardiography help predict risk
Official title: Risk Stratification and Prognostic Value of Right Ventricular Dysfunction Screening Using Transthoracic Echocardiography in Acute Pulmonary Embolism
Run by Sohag University · NCT07647497 · Data updated 2026-11-12
This study tests whether transthoracic echocardiography can identify right ventricular dysfunction in adults with acute pulmonary embolism to help gauge risk.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 112 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 2 sites (Sohag and 1 other locations) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT07647497 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older with confirmed acute pulmonary embolism who have undergone transthoracic echocardiography evaluating right ventricular function.
✕Probably not a fit
Patients without right ventricular dysfunction or without echocardiographic data may not derive prognostic benefit from these findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study uses transthoracic echocardiography to assess right ventricular function in patients with acute pulmonary embolism. The goal is to determine whether measures of RV dysfunction provide prognostic information and aid in risk stratification. Data are collected from adults with confirmed PE who had an echocardiographic assessment, focusing on the relationship between RV findings and outcomes. The lead site is Sohag University Hospital, with no listed collaborators. The study design is observational and does not involve an interventional treatment.
Why it matters
Potential benefit: If successful, findings could help clinicians stratify risk in acute PE using echocardiography-derived RV measures.
How similar studies have gone: Previous studies using echocardiographic assessment of RV function have shown prognostic value in PE, though this observational approach is less novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years and older. * Patients with a confirmed diagnosis of acute pulmonary embolism. * Patients who underwent transthoracic echocardiographic assessment for right ventricular dysfunction. Exclusion Criteria: * Patients younger than 18 years. * Patients with incomplete clinical data. * Patients who did not undergo transthoracic echocardiography.
Where it's running
-
Sohag University hospital
Sohag, Egypt Recruiting -
Sohag University hospital
Sohag, Egypt Not yet recruiting
Study contacts
- Study coordinator: Safiya Khalaf Abdallah, Assistant lecturer
- Email: olaamer2026@gmail.com
- Phone: 0201090720819
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
TRiP-cast score test in adults with acute lower-limb injuries requiring immobilization
This study tests whether the TRiP(cast) score can predict risk of blood clots in adults with acute lower-limb injuries treated as outpatients.
-
Prognostic value of the 2026 AHA/ACC PE classification in ED patients with acute PE
This study tests whether the 2026 AHA/ACC five-category PE classification helps predict 30-day major adverse pulmonary embolism events in adults with acute PE presenting to the ED.
-
Aspiration thrombectomy with the Symphony or Prodigy devices
This project will try the Symphony and Prodigy aspiration thrombectomy devices to remove arterial, venous, or pulmonary blood clots in adults.
-
PERC and YEARS approaches for diagnosing pulmonary embolism in the emergency department.
This project will test whether using the PERC score and the YEARS algorithm helps emergency doctors decide which adults need D-dimer blood tests or chest CT scans to diagnose pulmonary embolism.
-
Reperfusion options for acute pulmonary embolism
This project will try catheter-directed interventions or systemic thrombolysis in adults with acute pulmonary embolism to see which approach leads to better outcomes.
-
Evaluating anticoagulation duration for pulmonary embolism in ICU patients
This study is testing how long ICU patients with serious pulmonary embolism should be treated with blood thinners to see how well it helps them recover.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.