Evaluating anticoagulation duration for pulmonary embolism in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with clinically significant pulmonary embolism who are hospitalized in the intensive care unit. It aims to evaluate the duration of curative anticoagulation treatment, specifically using unfractionated heparin, and its effectiveness in managing this condition. The study will monitor the initiation of anticoagulation therapy and its outcomes based on various clinical parameters. Data will be collected from patients diagnosed with pulmonary embolism and treated with curative doses of anticoagulants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient (≥18 years old)
* Hospitalized in the intensive care unit of Hautepierre Hospital (Strasbourg University Hospitals UF 6250) between January 1, 2014, and December 31, 2023
* With a diagnosis of pulmonary embolism confirmed by a thoracic CT angiogram, a thoracoabdominopelvic CT scan, or a lung scan
* Having received anticoagulation with curative-dose unfractionated heparin

Exclusion Criteria:

* Subjects who have expressed objection to the reuse of their data for scientific research purposes. - Patients diagnosed with pulmonary embolism prior to admission to the intensive care unit and for whom we cannot precisely determine the start date of anticoagulation (precision estimated to the nearest hour).
* Pulmonary embolism not confirmed by contrast imaging (CT angiography)
* Patients who have not received curative anticoagulation (contraindication)
* Patients already receiving curative anticoagulation with UFH at the time of diagnosis
* Patients with low-risk pulmonary embolism defined by an sPESI score of 0
* Subject under court protection, guardianship, or curatorship

Where it's running

• Service de Réanimation Médicale - CHU de Strasbourg - France
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Vincent CASTELAIN, MD, PhD
• Email: vincent.castelain@chru-strasbourg.fr
• Phone: 33.3.88.12.79.15

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.