Reperfusion options for acute pulmonary embolism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

PE-NORDIC is a multicenter observational effort comparing outcomes for adults with acute pulmonary embolism who receive catheter-directed interventions (including mechanical thrombectomy devices such as FlowTriever® and catheter-directed thrombolysis) versus systemic thrombolysis. The study will collect real-world data from participating Nordic hospitals on survival, hemodynamic response, and bleeding complications. It is non-randomized and enrolls patients who are planned for or have already received these reperfusion methods, with a waiver of consent allowed if patients die before consent can be obtained. The project aims to describe how current reperfusion strategies perform in routine clinical practice across the region.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All adult patients (≥18 years), including pregnant women, with verified (CTPA, angiography or scintigraphy) acute pulmonary embolism who are planned for, or have received, treatment with catheter directed intervention or systemic thrombolysis
* Informed consent (for patients who do not survive before informed consent can be obtained, a waiver of consent applies)

Exclusion Criteria:

* Ongoing enrolment in interventional catheter directed intervention trial
* Surgical embolectomy as primary reperfusion treatment

Where it's running

• Aarhus University Hospital
  Aarhus, Denmark Recruiting
• Rigshospitalet
  Copenhagen, Denmark Recruiting
• Odense University Hospital
  Odense, Denmark Recruiting
• Sahlgrenska University Hospital
  Gothenburg, Sweden Recruiting
• Linköping University Hospital
  Linköping, Sweden Recruiting
• Sunderby Hospital
  Luleå, Sweden Recruiting

Study contacts

• Principal investigator: Kristina Svennerholm, Assoc Prof — Sahlgrenska University Hospital
• Study coordinator: Freyr Einarsson, MD
• Email: freyr.einarsson@vgregion.se
• Phone: +46500 43 10 36

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.