PERC and YEARS approaches for diagnosing pulmonary embolism in the emergency department.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Current diagnosis of pulmonary embolism typically uses clinical judgment followed by D-dimer testing and chest CT angiography, which can lead to overuse of imaging. The PERC rule and the YEARS algorithm are clinical decision tools designed to stratify risk and reduce unnecessary imaging by guiding when D-dimer or CT should be used. This observational analysis will include adults (≥18 years) seen in the Strasbourg University Hospital emergency department from January to June 2024 who had D-dimer testing and chest imaging, and will apply PERC and YEARS to those encounters. Main outcomes include potential reductions in CT angiography use, changes in emergency department waiting times, and the diagnostic yield of imaging when these algorithms are applied.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient (≥18 years)
* Patient admitted to the adult emergency department of the Strasbourg University Hospital over a 6-month period (January to June 2024), for whom a D-dimer test and chest imaging (thoracic CT angiography or ventilation/perfusion scintigraphy) were performed

Exclusion Criteria:

\- No D-dimer test or test performed for another indication, no chest imaging (CT angiography or scintigraphy), long-term anticoagulant treatment.

Where it's running

• Service d'Urgences Médico-Chirurgicales Adules - CHU de Strasbourg - France
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: François WEILL, MD
• Email: francois.weill@chru-strasbourg.fr
• Phone: 33 3.88.11.54.67

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.