Renal perfusion during minimally invasive abdominal surgery using ultrasound and NIRS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study will monitor renal perfusion in adults undergoing elective minimally invasive abdominal surgery. Measurements will be taken at predefined perioperative times using Doppler-derived Renal Resistive Index and NIRS-derived renal regional oxygen saturation to capture perfusion and oxygen delivery. The goal is to see how intraoperative factors like pneumoperitoneum and anesthesia affect kidney perfusion and whether these changes relate to postoperative acute kidney injury. Data will be analyzed in relation to intraoperative hemodynamics, intra-abdominal pressure, fluid management, urine output, and renal function after surgery. The study is single-center and will enroll adults aged 18 to 80 without contraindicating conditions who are undergoing procedures expected to last longer than one hour.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 to 80 years
* Patients with ASA physical status I, II, or III
* Patients undergoing elective minimally invasive abdominal surgery for any reason
* Patients whose expected surgical duration is longer than 1 hour

Exclusion Criteria:

* Body mass index greater than 35 kg/m²
* Severe respiratory system disease
* Severe heart failure, NYHA class III-IV
* Presence of a cardiac pacemaker or cardiac defibrillator implant
* Progressive neuromuscular disease
* High intra-abdominal pressure
* Sudden deterioration of general condition
* Incomplete clinical or laboratory data
* Refusal to participate in the study
* Conversion to open surgery

Where it's running

• Istanbul University Cerrahpaşa Faculty of Medicine
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Lyudmila MARTYNENKO AYDOGDU, M.D.
• Email: lyudmila.lylyly1@gmail.com
• Phone: +90 5300613611

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Remote Ischemic Preconditioning at Different Times After Heart Valve Surgery

  This study tests whether applying brief, controlled blood-flow restrictions to a limb at different times after heart valve surgery can help protect organs and reduce complications like kidney injury.

  Recruiting Fujian Medical University Union Hospital · Fuzhou, Fujian · NCT07888634

• Clinical decision support to help consider SGLT2 inhibitors after AKI in type 2 diabetes

  This pilot test checks if a CDS message given to clinicians can help decide whether to consider SGLT2 inhibitors for adults with type 2 diabetes who recently had acute kidney injury.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07868666

• Biomarkers to predict CSA-AKI risk before heart surgery

  This study tests new biomarkers to see if they can predict CSA-AKI risk in adults undergoing cardiovascular surgery.

  Recruiting China National Center for Cardiovascular Diseases · Beijing, Beijing Municipality · NCT07811570

• Reducing Endotoxin Burden in Septic Shock Patients on CRRT with the oXiris Filter

  This trial tests whether using the oXiris hemofilter during continuous kidney replacement helps lower endotoxin levels in adults with septic shock who need CRRT.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07807410

• Perioperative GFR Monitoring to Predict CSA-AKI and CA-AKI

  This study tests whether perioperative transcutaneous fluorescence GFR measurements can predict CSA-AKI or CA-AKI in adults undergoing cardiovascular procedures or iodine contrast exposure.

  Recruiting China National Center for Cardiovascular Diseases · Beijing, Beijing Municipality · NCT07749417

• Restarting RAS inhibitors after AKI: a quick test in hospitalized adults

  This pilot study tests whether restarting renin-angiotensin system inhibitors early after acute kidney injury is feasible and safe in hospitalized adults already using these medicines.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07734636

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.