Regular home use of dual-light antibacterial photodynamic therapy plus a powered toothbrush for older adults with periodontitis and mild cognitive impairment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized controlled trial, researchers compare three oral hygiene regimens over six months per participant (two years of data collection): standard care, a powered toothbrush alone, and Lumoral dual-light antibacterial photodynamic therapy combined with a manual toothbrush. The study measures plaque index, bleeding on probing, the number of deep pockets, intraoral halitosis, and oral health-related quality of life in adults with periodontitis stages I–III and MMSE 22–28. Participants are 60 years or older, have at least 15 teeth, and can provide informed consent, with exclusions including recent antibiotic use and certain medications. Blekinge Institute of Technology leads the trial with Blekinge County sites as locations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥60 years
* ≥15 teeth
* Diagnosed periodontitis stage I-III
* MMSE score between 22-28
* Able to provide informed consent

Exclusion Criteria:

* Antibiotic use (within 3 months)
* Lumoral use within 3 months
* Bisphosphonate medication
* Immunosuppressive drugs or radiation therapy

Where it's running

• Blekinge Tekniska Högskola
  Karlskrona, Blekinge County, Sweden Recruiting
• Blekinge Tekniska Högskola
  Karlskrona, Blekinge County, Sweden Not yet recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.