Registry to assess thromboembolic complications in COVID-19 patients

COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications (CORONA-VTE NET)

Observational Brigham and Women's Hospital · NCT04535128

This study looks at how often blood clots happen in COVID-19 patients and what factors might increase that risk to help improve prevention strategies.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
Ages18 Years and up
SexAll
SponsorBrigham and Women's Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT04535128 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze the frequency and risk factors of arterial and venous thromboembolic complications in patients diagnosed with COVID-19. By utilizing electronic health records, the study will evaluate the incidence of symptomatic venous thromboembolism (VTE) and related outcomes over 30 and 90 days. It will also identify independent risk factors for VTE that could inform thromboprophylaxis strategies during and after hospitalization. The study will involve a cohort of 10,000 patients across various U.S. healthcare settings.

Who should consider this trial

Good fit: Ideal candidates include patients who have tested positive for COVID-19 and are either hospitalized or receiving outpatient care.

Not a fit: Patients who have not been diagnosed with COVID-19 or those who are not receiving any form of management for the infection may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and management strategies for thromboembolic complications in COVID-19 patients.

How similar studies have performed: Other studies have indicated a significant association between COVID-19 and thromboembolic events, suggesting that this approach is grounded in emerging evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
1. Positive COVID-19 PCR AND
2. Inpatient OR outpatient management of COVID-19 infection

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Covid19Thrombosis EmbolismDVTPulmonary EmbolismMyocardial InfarctionStrokeCOVID-19Thromboembolism
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.