Registry for Spontaneous Coronary Artery Dissection
Official title: A Registry of Spontaneous Coronary Artery Dissection
Run by European Society of Cardiology · NCT06601270 · Data updated 2026-11-12
This study is setting up a large registry to collect information from women who have experienced spontaneous coronary artery dissection to better understand the condition and improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | European Society of Cardiology Research network |
| Locations | 73 sites (Buenos Aires and 72 other locations) |
| Status | Recruiting |
| Started | January 30, 2021 |
| Main results expected | October 2026 |
| Study ends | October 2027 |
| Registry record updated | October 29, 2024 |
| Trial ID | NCT06601270 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are patients aged 18 years and older who have been clinically diagnosed with SCAD within the past 10 years and have available coronary angiographic imagery.
✕Probably not a fit
Patients with iatrogenic or atherosclerotic coronary dissection will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish the first pan-European registry for spontaneous coronary artery dissection (SCAD), a condition that primarily affects young women without traditional heart disease risk factors. The registry will collect data from at least 500 prospectively recruited patients and 500 historical cases across approximately 30 countries and 120 sites. Patient data will be gathered at various time points, including the first SCAD event visit and yearly follow-ups for up to five years, to enhance understanding of SCAD management and inform clinical guidelines.
Why it matters
Potential benefit: If successful, this registry could lead to improved diagnosis and management of SCAD, ultimately enhancing patient outcomes.
How similar studies have gone: While there have been local and national registries for SCAD, this pan-European approach is novel and aims to fill a significant gap in understanding this condition.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient having signed an Informed Consent * Patient aged 18 years and over * SCAD clinical diagnosis within the past 10 years and available coronary angiographic imagery Exclusion Criteria: * Patient unwilling or unable to consent * Patients with iatrogenic or atherosclerotic coronary dissection
Where it's running
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ICBA - Instituto Cardiovascular de Buenos Aires
Buenos Aires, Argentina Recruiting -
Medical University of Innsbruck, Internal Medicine III
Innsbruck, Austria Recruiting -
Klinik Landstrasse
Vienna, Austria Recruiting -
Klinik Ottakring
Vienna, Austria Recruiting -
Medical University of Vienna
Vienna, Austria Recruiting -
Landesklinikum Wiener Neustadt
Wiener Neustadt, Austria Recruiting
Show 44 more locations
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AZ Sint jan, current president of Belgian ACCA
Bruges, Belgium Recruiting -
Cliniques Universitaires Saint-Luc (UCL)
Brussels, Belgium Recruiting -
Antwerp University Hospital
Edegem, Belgium Recruiting -
Ziekenhuis Oost Limburg, Interventional cardiology/Coronary Care
Genk, Belgium Recruiting -
Ghent University Hospital
Ghent, Belgium Recruiting -
CHR La Citadelle
Liège, Belgium Recruiting -
AZ Delta
Roeselare, Belgium Recruiting -
AZ Nikolaas
Sint-Niklaas, Belgium Recruiting -
Clinical Center University of Sarajevo
Sarajevo, Bosnia and Herzegovina Recruiting -
Hospital Israelita Albert Einstein
São Paulo, Brazil Recruiting -
Instituto do Coração do HCFMUSP
São Paulo, Brazil Recruiting -
Universidade Federal de São Paulo (UNIFESP)
São Paulo, Brazil Recruiting -
University Hospital of Split (KBC Split)
Split, Croatia Recruiting -
Nicosia General Hospital
Nicosia, Cyprus Recruiting -
Nemocnice Pardubického kraje
Pardubice, Czechia Recruiting -
Hospital Na Homolce
Prague, Czechia Recruiting -
Aarhus University Hospital
Aarhus, Denmark Recruiting -
Rigshospitalet
Copenhagen, Denmark Recruiting -
Herlev and Gentofte Hospital
Hellerup, Denmark Recruiting -
Odense University Hospital
Odense, Denmark Recruiting -
CHRU Jean Minjoz
Besançon, France Recruiting -
Gabriel Montpied Hospital - CHU Clermont-Ferrand
Clermont-Ferrand, France Recruiting -
Hôpital de Chartres Louis Pasteur
Le Coudray, France Recruiting -
Cardiovascular Hospital Louis Pradel - Hospices Civils de Lyon
Lyon, France Recruiting -
Hôpital Jacques Cartier
Massy, France Recruiting -
Hôpital Cardiologique du Haut Lévêque - Bordeaux University
Pessac, France Recruiting -
Schüchtermann-Klinik Bad Rothenfelde
Bad Rothenfelde, Germany Recruiting -
Vivantes Klinikum in Friedrichshain
Berlin, Germany Recruiting -
University Heart and Vascular Center Hamburg Eppendorf
Hamburg, Germany Recruiting -
Robert Bosch Hospital
Stuttgart, Germany Recruiting -
Sotiria Thoracic Diseases Hospital
Athens, Greece Recruiting -
General Hospital of Kozani
Kozani, Greece Recruiting -
Tehran Heart Center
Tehran, Iran Recruiting -
Papa Giovanni XXIII Azienda Ospedaliera
Bergamo, Italy Recruiting -
Policlinico Riuniti Foggia
Foggia, Italy Recruiting -
Ospedale Policlinico San Martino IRCCS, Genova & Università di Genova
Genoa, Italy Recruiting -
Presidio Ospedaliero Carlo Poma
Mantua, Italy Recruiting -
ASST Grande Ospedale Niguarda
Milan, Italy Recruiting -
Centro Cardiologico Monzino, IRCCS
Milan, Italy Recruiting -
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
Milan, Italy Recruiting -
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy Recruiting -
Noordwest Ziekenhuisgroep / NorthWest Clinics
Alkmaar, Netherlands Recruiting -
Amphia Hospital
Breda, Netherlands Recruiting -
Radboud University Medical Centre
Nijmegen, Netherlands Recruiting
+23 more sites. See ClinicalTrials.gov for the full list.
Study contacts
- Study coordinator: Adham GHARIEB, PharmD
- Email: agharieb@escardio.org
- Phone: 048-388-1770
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Survey of physical activity and quality of life for people with fibromuscular dysplasia
This national survey asks adults with fibromuscular dysplasia to see if activity restrictions affect their quality of life and emotional well-being.
-
Exercise responses in people with spontaneous coronary artery dissection or fibromuscular dysplasia
This study will test whether short sessions of different aerobic and resistance exercise change breathing, heart and blood pressure responses and symptoms in people with SCAD or FMD.
-
Stress contrast echocardiography in adults with prior SCAD
This project will use stress contrast echocardiography to see if small-vessel heart blood flow and blood-pressure responses during stress are different in adults who had spontaneous coronary artery dissection (SCAD) compared with healthy adults.
-
Remote exercise program after spontaneous coronary artery dissection
This study tests a remote exercise program to see if it’s doable for women recovering from SCAD events.
-
Analyzing the role of the sympathetic nervous system in spontaneous coronary artery dissection
This study is testing how the sympathetic nervous system affects heart health in people who have had spontaneous coronary artery dissection compared to similar individuals without the condition.
-
Observational study on spontaneous coronary artery dissection
This study is trying to learn more about spontaneous coronary artery dissection (SCAD) by following 3,000 patients over 10 years to better understand who it affects and how to treat it.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.