Clinical trial Recruiting at 2 sites Interventional Ages 50 to 80

Multilevel program to increase LDCT lung cancer screening and help African American smokers quit

Official title: Effectiveness of a Multilevel Integrated Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

Run by Louisiana State University Health Sciences Center in New Orleans · NCT07576595 · Data updated 2026-11-12

This program will try combining low-dose CT screening with culturally tailored smoking-cessation support to help African American smokers who are eligible for LDCT quit and get screened.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment250 (estimated)
SponsorLouisiana State University Health Sciences Center in New Orleans
Academic / other
Locations2 sites (New Orleans, Louisiana and 1 other locations)
StatusRecruiting
StartedApril 17, 2025
Main results expectedJune 2029
Study endsJune 2030
Registry record updatedMay 11, 2026
Trial IDNCT07576595 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English-speaking African American current smokers with at least a 20 pack-year history who are eligible for or have received LDCT screening.

Probably not a fit

People who are not current smokers, have less than a 20 pack-year history, or are not eligible for LDCT screening are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The intervention (MILS) integrates low-dose CT (LDCT) lung cancer screening with a multilevel, culturally tailored smoking cessation program using community-engaged methods and NIH DEIA-aligned strategies. The approach targets individual, interpersonal, and health-system determinants to increase screening uptake and promote sustained quitting among African American smokers with 20+ pack-years. Outcomes include LDCT uptake, smoking cessation rates, and measures of reach and acceptability within the targeted communities. The program is implemented at LSUHSC School of Public Health and University Medical Center in New Orleans and uses coordinated clinical and community resources.

Why it matters

Potential benefit: If successful, the intervention could increase LDCT screening and quit rates among African American smokers and help reduce lung cancer disparities.

How similar studies have gone: Previous work shows LDCT can serve as a teachable moment that increases quit attempts, but comprehensive, culturally tailored multilevel programs for African Americans are limited, so this integrated approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* African American
* 20+ pack years of smoking
* eligible for or received LDCT screening
* current smoker
* English speaking

Exclusion Criteria:

* N/A

Where it's running

  • LSUHSC School of Public Health
    New Orleans, Louisiana, United States
    Recruiting
  • University Medical Center
    New Orleans, Louisiana, United States
    Recruiting

Study contacts

  • Principal investigator: Tung Sung Tseng, DrPH, MS — LSUHSC New Orleans
  • Study coordinator: Jessica Kassner, MS, MPH
  • Email: jkassn@lsuhsc.edu
  • Phone: 504-568-5724

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.