Multilevel program to increase LDCT lung cancer screening and help African American smokers quit

Effectiveness of a Multilevel Integrated Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

Not applicable Interventional Louisiana State University Health Sciences Center in New Orleans · NCT07576595

This program will try combining low-dose CT screening with culturally tailored smoking-cessation support to help African American smokers who are eligible for LDCT quit and get screened.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages50 Years to 80 Years
SexAll
SponsorLouisiana State University Health Sciences Center in New Orleans Academic / other
Locations2 sites (New Orleans, Louisiana and 1 other locations)
Trial IDNCT07576595 on ClinicalTrials.gov

What this trial studies

The intervention (MILS) integrates low-dose CT (LDCT) lung cancer screening with a multilevel, culturally tailored smoking cessation program using community-engaged methods and NIH DEIA-aligned strategies. The approach targets individual, interpersonal, and health-system determinants to increase screening uptake and promote sustained quitting among African American smokers with 20+ pack-years. Outcomes include LDCT uptake, smoking cessation rates, and measures of reach and acceptability within the targeted communities. The program is implemented at LSUHSC School of Public Health and University Medical Center in New Orleans and uses coordinated clinical and community resources.

Who should consider this trial

Good fit: Ideal candidates are English-speaking African American current smokers with at least a 20 pack-year history who are eligible for or have received LDCT screening.

Not a fit: People who are not current smokers, have less than a 20 pack-year history, or are not eligible for LDCT screening are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the intervention could increase LDCT screening and quit rates among African American smokers and help reduce lung cancer disparities.

How similar studies have performed: Previous work shows LDCT can serve as a teachable moment that increases quit attempts, but comprehensive, culturally tailored multilevel programs for African Americans are limited, so this integrated approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* African American
* 20+ pack years of smoking
* eligible for or received LDCT screening
* current smoker
* English speaking

Exclusion Criteria:

* N/A

Where this trial is running

New Orleans, Louisiana and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung Cancer ScreeningTobacco Use DisorderSmoking CessationAfrican AmericanHealth DisparitiesTobacco UseLow-Dose Computed TomographyLDCT
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.