Empowering patients to get lung cancer screening with support and navigation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized pilot compares enhanced usual care to Empower LCS/Call+ for adults eligible for USPSTF lung cancer screening. The intervention combines patient education, provider reminders, and information about financial and community resources, with a follow-up Call+ telephone navigation for those who don’t complete screening initially. About 80 participants will be enrolled from UC Irvine Health and Emory Healthcare. Outcomes focus on screening uptake, timing, and barriers encountered. The study uses lay navigators to address patient-specific obstacles and facilitate scheduling when appropriate.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Must meet current USPSTF eligibility criteria for lung cancer screening (Current criteria: age 50-80 years old with a 20 pack-year smoking history, who currently smoke or have quit within the last 15 years)
2. Must have an electronic health record-assigned primary care provider within University of California Irvine Health or Emory Healthcare
3. Must have recent engagement with respective health system (i.e., office or emergency department (ED) visit, hospitalization with discharged home in the last 12 months, or a scheduled office visit in the next 3 months).
4. Must speak English or Spanish
5. Able and willing to provide informed consent

Exclusion Criteria:

1. Meet the eligibility upper age limit during initial 4-month participation.
2. Have a prior history of lung cancer.
3. Have a new diagnosis of other cancers in the 12 months
4. Have a chest CT or LDCT in the last 12 months
5. Have ICD-10 code of Alzheimer's disease in EHR

Where it's running

• UCI Health Family Health Center - Anaheim
  Anaheim, California, United States Recruiting
• UCI Health - Costa Mesa
  Costa Mesa, California, United States Recruiting
• CHAO Family Comprehensive Cancer Center- Irvine
  Irvine, California, United States Recruiting
• UCI Health Gottschalk Medical Plaza
  Irvine, California, United States Recruiting
• UCI Health - Laguna Hills
  Laguna Hills, California, United States Recruiting
• UCI Health - Newport Beach MacArthur
  Newport Beach, California, United States Recruiting

+7 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Principal investigator: Gelareh Sadigh — University of California, Irvine
• Study coordinator: Gelareh Sadigh, MD
• Email: gsadigh@hs.uci.edu
• Phone: (714) 456-3610

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.