Probiotic Y7 cocktail to help with early Parkinson’s symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial uses preclinical human work to guide a two-arm randomized design, comparing the Y7 probiotic cocktail to placebo in adults with early-stage Parkinson’s disease. It will recruit about 120 participants (Hoehn and Yahr stages 1–3) and measure motor function, cognition, and non-motor symptoms as outcomes. The study will collect clinical data, biomarkers, and questionnaires to build a personalized prognosis model while evaluating any potential delay in disease progression. If results are favorable, the program may advance toward commercial development. The sponsor is Taipei Medical University, with participating hospitals in Taipei.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Subject Inclusion Criteria:

1. Age between 30-85 years old.
2. Diagnosed with early-stage Parkinson's disease (Hoehn and Yahr scale stage 1-3).
3. Brain MRI confirms striatal degeneration in the basal ganglia region, with no history of stroke.
4. Responds to Parkinson's disease-related medications (e.g., Levodopa).
5. Free of any major or acute illnesses.
6. Able to comply with the 12 weeks intervention and required assessments for the study.

Exclusion Criteria:

1. Unable to complete interviews or has mobility issues.
2. Presence of major or acute illness before or during the study.
3. Co-existing intestinal co-infections, such as CDI, E. coli, Salmonella, Shigella, Campylobacter, plague, or cytomegalovirus.
4. Allergic to the intervention product.
5. Pregnant or breastfeeding women.

Where it's running

• Taipei Medical University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Hui Yu Huang, PhD
• Email: maggieh323@tmu.edu.tw
• Phone: 02-27361661

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.