Clinical trial Recruiting at 1 site Interventional Ages 18 to 55

Barley and kefir to support gut health in active adults

Official title: Effects of a Four-Week Dietary Intervention With Barley and Kefir on Gut Microbiota, Circulating Metabolites, and Health Outcomes in Physically Active Adults: A Randomized Controlled Trial

Run by Western Norway University of Applied Sciences · NCT07864779 · Data updated 2026-11-12

This study tests whether a daily barley and kefir meal for four weeks can change gut microbiota in physically active adults and whether those changes relate to certain metabolites in blood and urine.

Quick facts

Study typeInterventional
Ages18 Years to 55 Years
SexAll
Enrollment80 (estimated)
SponsorWestern Norway University of Applied Sciences
Academic / other
Locations1 site (Bergen)
StatusRecruiting
StartedSeptember 7, 2026
Main results expectedJune 2031
Study endsJune 2031
Registry record updatedOctober 23, 2026
Trial IDNCT07864779 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–55 who engage in endurance-type activities and have high VO2max values as defined in the criteria, without milk allergy, lactose intolerance, or recent antibiotic use.

Probably not a fit

Individuals with dairy intolerance or milk allergy, or those recently treated with antibiotics, may not experience benefit from this barley-kefir intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial evaluates a practical four-week dietary intervention using barley and kefir to modulate gut microbiota in endurance athletes or active adults. Participants will consume a daily meal containing barley and kefir, with analysis of gut microbiota diversity and composition before and after the intervention, alongside circulating and urinary metabolite measurements. The study aims to link diet-induced microbial changes to metabolomic profiles, shedding light on how everyday foods may influence metabolism and health in active individuals. Eligibility targets adults aged 18–55 with high aerobic capacity, excluding those with conditions or allergies that affect gut health or dairy intake. The lead sponsor is Western Norway University of Applied Sciences, with the trial conducted at their Bergen campus.

Why it matters

Potential benefit: If successful, the intervention could offer a practical dietary approach to promote a healthier gut microbiota in active adults and potentially support metabolic health.

How similar studies have gone: Previous work suggests diet can influence gut microbiota, but applying barley and kefir in athletic populations is relatively novel and its effects are not yet proven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 - 55 years
* High aerobic capacity defined by the following minimum estimated VO₂max values:

Men:

* 20-29 years: ≥ 51 mL/kg/min
* 30-39 years: ≥ 47 mL/kg/min
* 40-49 years: ≥ 43 mL/kg/min
* 50-55 years: ≥ 38 mL/kg/min

Women:

* 20-29 years: ≥ 44 mL/kg/min
* 30-39 years: ≥ 40 mL/kg/min
* 40-49 years: ≥ 36 mL/kg/min
* 50-55 years: ≥ 32 mL/kg/min

Exclusion Criteria:

* Pregnancy
* Ulcerative colitis
* Crohn's disease
* Coeliac disease
* Milk allergy
* Lactose intolerance
* Use of antibiotics within the previous 6 months

Where it's running

  • Western Norway University of Applied Sciences
    Bergen, Norway
    Recruiting

Study contacts

  • Principal investigator: Iselin T Vildmyren, PhD — Western Norway University of Applied Sciences
  • Study coordinator: Iselin T Vildmyren, PhD
  • Email: isvi@hvl.no
  • Phone: +4798699287

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.