Clinical trial Recruiting at 1 site Observational Ages 60 and up

Preoperative Muscle Health and Postoperative Outcomes in Older Adults with GI Cancer

Official title: The Effect of Preoperative Sarcopenia on Postoperative Prognosis in Older Patients With Gastrointestinal Cancer: A Prospective Cohort Study

Run by Van Training and Research Hospital · NCT07817758 · Data updated 2026-11-12

This study looks at whether having sarcopenia before surgery affects recovery and complications after GI cancer surgery in people 60 and older.

More Sarcopenia trials

Quick facts

Study typeObservational
Ages60 Years and up
SexAll
Enrollment100 (estimated)
SponsorVan Training and Research Hospital
Government
Locations1 site (Van, Van)
StatusRecruiting
StartedJune 1, 2026
Main results expectedJune 1, 2027
Study endsJuly 1, 2027
Registry record updatedSeptember 14, 2026
Trial IDNCT07817758 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 60 or older with gastrointestinal cancer scheduled for elective surgery and able to complete sarcopenia assessments.

Probably not a fit

Patients without preoperative sarcopenia or those not undergoing surgery may not see a direct benefit from this observational study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational cohort study enrolling adults 60 years and older who are scheduled for elective gastrointestinal cancer surgery. Researchers will assess preoperative sarcopenia using EWGSOP2 criteria (strength, mass, and performance), plus SARC-F and calf measurements, to see if sarcopenia is linked to postoperative complications, length of stay, and 30- or 90-day mortality. Participants will be followed for 90 days after surgery, with standard perioperative care. The study will compare outcomes between those with and without preoperative sarcopenia to determine if sarcopenia is independently associated with worse postoperative results.

Why it matters

Potential benefit: If preoperative sarcopenia is linked to poorer outcomes, these findings could inform risk stratification and perioperative planning for older GI cancer patients.

How similar studies have gone: Prior research in older surgical populations suggests sarcopenia can be associated with worse outcomes, but evidence specific to GI cancer surgery is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 60 years or older
* Diagnosis of gastrointestinal system cancer
* Scheduled to undergo elective surgical treatment
* Considered operable based on routine clinical evaluation
* Ability to complete the preoperative sarcopenia assessments
* Provision of written informed consent

Exclusion Criteria:

* Age younger than 60 years
* Undergoing emergency surgery
* Inability to complete the required preoperative sarcopenia assessment

Where it's running

  • Van Education and Research Hospital
    Van, Van, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.