Pre-incisional ropivacaine plus diprospan to relieve pain after VATS
Official title: The Efficacy and Safety of Pre-incisional Infiltration With Ropivacaine Plus Diprospan in Patients Undergoing Video-assisted Thoracoscopic: a Multi-center Randomized Controlled Trial.
Run by Beijing Tiantan Hospital · NCT07626489 · Data updated 2026-11-12
This study tests whether injecting ropivacaine with diprospan before surgery can reduce postoperative pain for adults and children undergoing VATS lung surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 64 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Beijing Tiantan Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | May 30, 2026 |
| Main results expected | May 31, 2027 |
| Study ends | May 30, 2028 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT07626489 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 8–64 years with ASA I–III undergoing elective VATS procedures (wedge resection, segmentectomy, or lobectomy) who can consent and adhere to follow-up.
✕Probably not a fit
Patients with allergies to opioids or steroids, significant organ dysfunction, or those unable to use pain scales may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates a pre-incisional infiltration strategy using ropivacaine plus diprospan in patients undergoing video-assisted thoracoscopic surgery for wedge resection, segmentectomy, or lobectomy. The goal is to see if this approach lowers acute postoperative pain and improves recovery by reducing inflammatory pain at the surgical site. Eligible participants are adults or adolescents aged 8 to 64 years with ASA I–III undergoing elective VATS under general anesthesia. The trial is conducted at Beijing Tiantan Hospital and aims to inform whether this analgesic combination can be a standard option for perioperative pain control in thoracic procedures.
Why it matters
Potential benefit: If successful, patients may experience less postoperative pain and faster recovery after VATS.
How similar studies have gone: Previous thoracic analgesia approaches with local anesthetics and adjuvants have shown pain reduction in some settings, but results vary and this exact combination is not yet established practice in VATS.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients scheduled for elective Video-assisted thoracoscopic surgery for wedge resection, segmentectomy and lobectomy of the lungs under general anesthesia; 2. 8 to 64 years old 3. American Society of Anesthesiologists (ASA) physical status of I-III 4. Patients must be able to understand the nature and potential personal consequences of the clinical trial and cooperate with follow-up investigations 5. signing of the informed consent form. Exclusion Criteria: 1. History of allergies to experimental drugs such as opioids or steroids; 2. Alcohol abuse; Long term use of opioid drugs (exceeding 2 weeks or 3 days per week for more than 1 month); Suspected use of sedatives and analgesics; Use analgesic drugs within 24 hours before surgery; Patients undergoing steroid therapy; 3. Serious neurological disorders, severe liver and kidney dysfunction, heart failure, etc; 4. Unable to use pain assessment scale; 5. Pregnant or lactating patients.
Where it's running
-
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Fang Luo
- Email: 13611326978@163.com
- Phone: +86 13611326978
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Infiltration with ropivacaine plus triamcinolone to relieve pain after VATS surgery
This study tests whether injecting ropivacaine with or without triamcinolone before incision can reduce pain after thoracoscopic lung surgery in adults.
-
Using auricular acupressure to improve health before lung surgery
This study is testing whether auricular acupressure can help improve the health and well-being of people aged 50 and older who are getting ready for major lung surgery.
-
Force feedback in robotic lung resection: does gentler instrument touch help recovery?
This study tests whether using Force Feedback instruments during robotic lobectomy or segmentectomy leads to faster recovery and fewer complications for adults undergoing these procedures.
-
Personalized pain management after thoracic surgery
This study is testing a new way to manage pain after lung surgery to see if personalized plans can help patients feel better and use fewer opioids.
-
Visual feedback in inspiratory muscle training after lobectomy
This study tests whether adding a mobile app with visual feedback to inspiratory muscle training helps lung cancer patients after lobectomy by improving motivation, adherence, and comfort while breathing.
-
Pre-incisional ropivacaine plus Diprospan for pain after laparoscopic surgery
This study tests whether injecting ropivacaine with Diprospan before surgery reduces pain after laparoscopic gallbladder, appendix, or hernia operations compared with ropivacaine alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.