Clinical trial Recruiting at 1 site Interventional Ages 18 to 64

Pre-incisional ropivacaine plus diprospan to relieve pain after VATS

Official title: The Efficacy and Safety of Pre-incisional Infiltration With Ropivacaine Plus Diprospan in Patients Undergoing Video-assisted Thoracoscopic: a Multi-center Randomized Controlled Trial.

Run by Beijing Tiantan Hospital · NCT07626489 · Data updated 2026-11-12

This study tests whether injecting ropivacaine with diprospan before surgery can reduce postoperative pain for adults and children undergoing VATS lung surgery.

Quick facts

Study typeInterventional
Ages18 Years to 64 Years
SexAll
Enrollment100 (estimated)
SponsorBeijing Tiantan Hospital
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedMay 30, 2026
Main results expectedMay 31, 2027
Study endsMay 30, 2028
Registry record updatedJune 17, 2026
Trial IDNCT07626489 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 8–64 years with ASA I–III undergoing elective VATS procedures (wedge resection, segmentectomy, or lobectomy) who can consent and adhere to follow-up.

Probably not a fit

Patients with allergies to opioids or steroids, significant organ dysfunction, or those unable to use pain scales may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates a pre-incisional infiltration strategy using ropivacaine plus diprospan in patients undergoing video-assisted thoracoscopic surgery for wedge resection, segmentectomy, or lobectomy. The goal is to see if this approach lowers acute postoperative pain and improves recovery by reducing inflammatory pain at the surgical site. Eligible participants are adults or adolescents aged 8 to 64 years with ASA I–III undergoing elective VATS under general anesthesia. The trial is conducted at Beijing Tiantan Hospital and aims to inform whether this analgesic combination can be a standard option for perioperative pain control in thoracic procedures.

Why it matters

Potential benefit: If successful, patients may experience less postoperative pain and faster recovery after VATS.

How similar studies have gone: Previous thoracic analgesia approaches with local anesthetics and adjuvants have shown pain reduction in some settings, but results vary and this exact combination is not yet established practice in VATS.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients scheduled for elective Video-assisted thoracoscopic surgery for wedge resection, segmentectomy and lobectomy of the lungs under general anesthesia;
2. 8 to 64 years old
3. American Society of Anesthesiologists (ASA) physical status of I-III
4. Patients must be able to understand the nature and potential personal consequences of the clinical trial and cooperate with follow-up investigations
5. signing of the informed consent form.

Exclusion Criteria:

1. History of allergies to experimental drugs such as opioids or steroids;
2. Alcohol abuse; Long term use of opioid drugs (exceeding 2 weeks or 3 days per week for more than 1 month); Suspected use of sedatives and analgesics; Use analgesic drugs within 24 hours before surgery; Patients undergoing steroid therapy;
3. Serious neurological disorders, severe liver and kidney dysfunction, heart failure, etc;
4. Unable to use pain assessment scale;
5. Pregnant or lactating patients.

Where it's running

  • Beijing Tiantan Hospital
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.