Clinical trial Recruiting at 1 site Observational Ages 18 and up

Personality Traits and Biochemical Risk Markers in Routine Health Assessments

Official title: Personality Traits and Biochemical Risk Phenotypes in Adults Undergoing Routine Health Assessment

Run by Medical Center TOPMED · NCT07653048 · Data updated 2026-11-12

This study tests whether personality traits relate to the number of abnormal lab results found during a standard health checkup in adults.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorMedical Center TOPMED
Academic / other
Locations1 site (Târgu Mureş, Mureș County)
StatusRecruiting
StartedOctober 1, 2024
Main results expectedJanuary 1, 2027
Study endsSeptember 1, 2027
Registry record updatedJune 17, 2026
Trial IDNCT07653048 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older undergoing routine health assessments who have completed the FFPI and have available laboratory data with informed consent.

Probably not a fit

Patients without complete FFPI data or missing laboratory results may not contribute to the primary analyses.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational cohort study conducted in adults undergoing routine health assessments. Participants complete the Five-Factor Personality Inventory (FFPI) and have routine laboratory tests measured, including glycemic markers, liver enzymes, lipids, kidney function, and blood counts. The primary goal is to see if FFPI scores are associated with the total count of laboratory abnormalities. Secondary analyses explore links between personality traits and specific measures such as fasting glucose, liver function markers, lipids, renal markers, and CBC parameters. Data are collected from standard clinical evaluations to identify potential biochemical risk patterns in relation to personality profiles.

Why it matters

Potential benefit: If successful, findings could improve understanding of how personality-related factors relate to biochemical risk profiles identified in routine care.

How similar studies have gone: Prior studies have explored associations between psychological traits and biological markers, but this specific FFPI-to-laboratory-abnormalities link in routine health checks is relatively novel and not yet established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 years or older
* Undergoing routine health assessment
* Completion of the Five-Factor Personality Inventory (FFPI)
* Availability of routine laboratory test results
* Provision of written informed consent

Exclusion Criteria:

* Age younger than 18 years
* Incomplete FFPI assessment
* Missing or incomplete laboratory data
* Refusal or inability to provide informed consent

Where it's running

  • Medical Center TOPMED
    Târgu Mureş, Mureș County, Romania
    Recruiting

Study contacts

  • Principal investigator: Stefania Diana St Nilca, Principal Psychologist, PhD St — George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș
  • Study coordinator: Stefania Diana St Nilca, Principal Psychologist, PhD St
  • Email: diana.nilca@umfst.ro
  • Phone: +40745404037

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.