Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Pain relief for patients undergoing jaw surgery

Official title: Effect of Combined Maxillary and Mandibular Nerve Block on Orthognathic Surgery Outcomes

Run by Mansoura University · NCT05925465 · Data updated 2026-11-12

This study is testing if nerve blocks can help reduce pain for patients having jaw surgery, especially those with jaw fractures, during their recovery.

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment60 (estimated)
SponsorMansoura University
Academic / other
Locations1 site (Al Mansurah, Mansoura)
StatusRecruiting
StartedAugust 1, 2023
Main results expectedDecember 28, 2027
Study endsMarch 31, 2028
Registry record updatedFebruary 17, 2026
Trial IDNCT05925465 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are ASA I/II patients aged 21-60 years scheduled for elective faciomaxillary surgery.

Probably not a fit

Patients who are pregnant, have polytrauma, or require postoperative ventilation will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of maxillary and mandibular nerve blocks in providing analgesia for patients undergoing elective faciomaxillary surgery, particularly for those with mandibular fractures. The study aims to evaluate the pain relief provided by these nerve blocks during the critical postoperative period, which is often associated with significant discomfort. By comparing the analgesic effects of the nerve blocks to a control group, the trial seeks to determine the potential benefits of this intervention in managing postoperative pain.

Why it matters

Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery for patients undergoing jaw surgery.

How similar studies have gone: There have been few studies evaluating the analgesic effects of nerve blocks in maxillofacial surgeries, indicating that this approach may be novel or underexplored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) I/II patients,
* within the age group of 21-60 years
* both sex
* scheduled for elective faciomaxillary surgery

Exclusion Criteria:

* Pregnant or breast-feeding women
* Patients with polytrauma
* Patients necessitating postoperative ventilation
* Oral or facial infection
* Coagulopathy
* Drug intake for chronic pain
* Known allergy to the study drugs
* Psychiatric disorder

Where it's running

  • Maha Ahmed AboZeid
    Al Mansurah, Mansoura, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.