Ozoaqua scar care after open abdominal surgery compared with standard care
Official title: Prospective, Randomized, Evaluator-blinded Clinical Study to Compare a Post-surgical Scar Care Protocol Using OzoAqua Products Versus Standard Care in Open Abdominal Surgery.
Run by Laboratorios Ozoaqua · NCT07678372 · Data updated 2026-11-12
This study tests if adding Ozoaqua products after open abdominal surgery improves the scar quality at 3 months compared with usual care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 144 (estimated) |
| Sponsor | Laboratorios Ozoaqua Industry-sponsored |
| Locations | 2 sites (Pamplona, Navarre and 1 other locations) |
| Status | Recruiting |
| Started | August 14, 2026 |
| Main results expected | July 6, 2027 |
| Study ends | July 6, 2027 |
| Registry record updated | October 30, 2026 |
| Trial ID | NCT07678372 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults undergoing scheduled open abdominal surgery with primary wound closure and an assessable linear abdominal scar.
✕Probably not a fit
Patients who do not respond to topical scar care or who have factors that predispose to poor wound healing despite intervention may not see a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, randomized study compares a postoperative scar care protocol using ozonated Ozoaqua products to standard care in adults undergoing open abdominal surgery. A blinded evaluator will assess scar quality at 3 months, while treatment is open-label due to the topical nature of the intervention. The study is single-center, with 1:1 randomization to either standard care plus Ozoaqua or standard care alone, and includes preoperative consent, daily in-hospital wound assessments, and follow-up visits at 2 weeks and 1 month. Primary outcome is scar quality at 3 months, with safety and adherence monitored throughout the perioperative period.
Why it matters
Potential benefit: If successful, patients could experience improved scar appearance and healing with a simple topical regimen after open abdominal surgery.
How similar studies have gone: Other wound-care studies using topical agents show variable scar outcomes; this trial investigates a specific ozonated protocol in a similar surgical context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years * Scheduled open abdominal surgery * Primary wound closure * Assessable linear abdominal scar * Signed informed consent * Ability to complete 3-month follow-up Exclusion Criteria: * Known allergy to treatment components * Active infection or significant dehiscence in the immediate postoperative period * Planned use of specific scar treatments -silicone products, laser therapy, local corticosteroids- except as clinical rescue treatment * Inability to complete follow-up * Participation in another study that may interfere with wound healing
Where it's running
-
Clínica Universidad de Navarra
Pamplona, Navarre, Spain Recruiting -
Clínica Universidad de Navarra, sede Madrid
Madrid, Spain Recruiting
Study contacts
- Study coordinator: Juan Gabriel Agüera Santos
- Email: juan.aguera@bioithas.com
- Phone: +34 623 02 25 86
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.