Ovarian Reserve After Cystectomy for Endometriotic vs. Non-Endometriotic Cysts

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls women aged 18-45 with ovarian cysts scheduled for laparoscopic cystectomy to compare changes in ovarian reserve between endometriotic and non-endometriotic cysts. Preoperative AMH, antral follicle count, and FSH are measured within one month before surgery. Intraoperative data such as operative time, blood loss, cyst laterality, and cauterization details are collected. Postoperative follow-up focuses on initial ovarian function markers and safety data collected by trained staff at Benha University hospitals. Eligible participants must have cysts 6-15 cm, AMH ≥ 2 ng/mL, and consent to participate.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients aged 18-45 years
* Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI
* Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis
* Serum anti-Müllerian hormone (AMH) level ≥ 2 ng/mL, measured within 1 month preoperatively
* Willingness to participate and provide written informed consent

Exclusion Criteria:

* Clinical or ultrasonic suspicion of ovarian malignancy
* Ovarian cyst associated with pregnancy
* Previous history of ovarian surgery
* History of pelvic irradiation or chemotherapy
* Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia)
* Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment
* Presence of severe systemic disease that contraindicates surgery or general anesthesia
* Refusal to participate or inability to provide informed consent

Where it's running

• Benha Univesity Hospital
  Banhā, Qalyubia Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Ahmed Alnezamy, Md — Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Benha University
• Study coordinator: Ahmed Alnezamy, Md
• Email: AHMED.ALNZAMY@fmed.bu.edu.eg
• Phone: 01224849065

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Imaging endometriosis with a special PET tracer in adult women

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.