Clinical trial Recruiting at 1 site Interventional Ages 25 to 38 Women only

How AMH testing and AI counseling might help women plan family and ease fertility worries

Official title: Women Rise, Families Thrive: Advancing Women's Health and Fertility Awareness Through Ovarian Reserve Assessment in Hong Kong

Run by City University of Hong Kong · NCT07894302 · Data updated 2026-11-12

This study tests whether AMH blood testing plus AI-guided counseling or traditional education can improve fertility understanding and reduce anxiety among women aged 25–38 in Hong Kong.

More Diminished Ovarian Reserve trials

Quick facts

Study typeInterventional
Ages25 Years to 38 Years
SexWomen only
Enrollment600 (estimated)
SponsorCity University of Hong Kong
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Hong Kong, Kowloon)
StatusRecruiting
StartedMarch 31, 2026
Main results expectedMay 30, 2027
Study endsDecember 31, 2027
Registry record updatedOctober 26, 2026
Trial IDNCT07894302 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Biologically female individuals aged 25–38 who are fluent in Chinese or English and have internet access, with no pregnancy, breastfeeding, major psychiatric/cognitive illness, gynecological cancer history, or current gonadotoxic treatment.

Probably not a fit

Participants without improvements in comprehension or anxiety reduction may not experience benefit from the intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines whether preventive ovarian reserve screening using AMH testing, combined with AI-enabled counseling, improves fertility knowledge and lowers reproductive anxiety compared with standard health education. Participants are 25 to 38 years old women in Hong Kong, allocated to AMH testing with AI counseling delivered by an interactive agent or a static report, versus standard education alone. The design uses a 2x2 framework with propensity score matching and randomized elements to compare comprehension, anxiety, and reproductive intentions at baseline and 2–4 weeks follow-up. Outcomes include medical understanding, STAI-6 anxiety scores, and patient enablement. The trial aims to inform future public health screening policies and addressing psychological barriers to family planning.

Why it matters

Potential benefit: If successful, participants may achieve greater clarity about fertility status and reduced anxiety, potentially supporting informed family planning decisions.

How similar studies have gone: Previous work suggests AI-enabled health communication can improve understanding, but this approach combining AMH screening with AI counseling in this context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Biologically female (assigned female at birth, with intact ovaries)
* Aged 25 to 38 years
* Fluent in written and spoken Chinese (Traditional or Simplified) or English
* Has access to an internet-enabled smartphone or computer
* Able to give electronic or written informed consent

Exclusion Criteria:

* Currently pregnant or breastfeeding
* Known active, severe psychiatric or cognitive disorder that prevents informed - consent or completing the questionnaire
* History of gynecological cancer
* Currently receiving gonadotoxic chemotherapy or pelvic radiotherapy

Where it's running

  • City University of Hong Kong
    Hong Kong, Kowloon, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.