Orthobiological Therapies for Musculoskeletal Conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This early-phase study prospectively records clinical and functional outcomes after orthobiological treatments used in routine care for musculoskeletal conditions. It aims to identify patterns of efficacy by agent type, pathology, and follow-up time, while monitoring safety under defined clinical criteria. Data will come from patients treated at the Proregen Medical Clinic and affiliates, with standardized questionnaires and routine clinical assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 or older;
* Clinical and/or radiological diagnosis of an eligible musculoskeletal condition;
* Formal clinical indication for treatment with orthobiological agents, according to routine care;
* Regular access to the WhatsApp application, ensuring the necessary communication for sending and receiving digital questionnaires and other study instructions;
* Ability to understand the study and sign the Informed Consent Form.

Exclusion Criteria:

* Medical contraindication to the use of orthobiologics (e.g., active infection, severe hematological diseases, active cancer);
* Recent use (≤3 months) of orthobiologic therapies in the same area to be treated;
* Pregnant or breastfeeding women;
* Cognitive or psychiatric diseases that prevent adequate clinical follow-up;
* Simultaneous participation in another interventional clinical study with the same therapeutic purpose.

Where it's running

• Clínica Proregen | Clínica Ortopédica em Bento | Dr. André Kruel
  Bento Gonçalves, Rio Grande do Sul, Brazil Recruiting

Study contacts

• Study coordinator: Gabriela D Daiprai
• Email: gdaiprai@universo.univates.br
• Phone: 51995342193

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.