Clinical trial Recruiting at 2 sites Interventional Ages 19 and up

Evaluating stress management's impact on musculoskeletal health in employees

Official title: Musculoskeletal Disorders and Stress Management, in Employees

Run by University of Thessaly · NCT06488547 · Data updated 2026-11-12

This study is testing if a six-week stress management program can help employees feel better physically and reduce time off work due to muscle and joint pain caused by stress.

More Musculoskeletal Pain trials

Quick facts

Study typeInterventional
Ages19 Years and up
SexAll
Enrollment57 (estimated)
SponsorUniversity of Thessaly
Academic / other
Locations2 sites (Larissa, Biopolis- Larissa and 1 other locations)
StatusRecruiting
StartedJune 1, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedJuly 5, 2024
Trial IDNCT06488547 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are employees who can read and write Greek and are willing to provide their medical history.

Probably not a fit

Patients close to retirement, those with diagnosed musculoskeletal injuries, or those on specific medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between work-related stress and musculoskeletal health in employees by measuring biological stress markers such as saliva cortisol, heart rate variability, and electromyography. Participants will be divided into two groups, with one group receiving a six-week stress management intervention that includes techniques like diaphragmatic breathing and progressive muscle relaxation. The study aims to assess whether these interventions can improve self-reported musculoskeletal health and reduce work absences due to related conditions. Outcomes will be measured through self-report questionnaires and stress biomarkers at the beginning and end of the intervention period.

Why it matters

Potential benefit: If successful, this study could lead to improved musculoskeletal health and reduced work-related stress for employees.

How similar studies have gone: Other studies have shown promise in using stress management techniques to improve health outcomes, suggesting this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Writing and reading greek.
* Consent to provide their medical history.
* Consent to be measured with electronic devices.

Exclusion Criteria:

* Employees who are close to retirement (at least 2 years before) and those for whom any known factor may prevent them from completing the intervention (eg travel, transfer).
* Pregnancy.
* Pacemaker, history of seizures.
* Diagnosed musculoskeletal injury.
* Diagnosed diseases such as: osteoarthritis, autoimmune diseases (rheumatoid arthritis, lupus, etc.), stroke, myocardial infarction, malignant neoplasms, psychiatric disease, disability.
* Systematic reception of cortisone and anti-inflammatory treatment, up to at least three months before the intervention.
* Drugs or substances.
* Participation in another interventional program of musculoskeletal rehabilitation, physical therapy, stress management or health promotion.

Where it's running

  • University of Thessaly
    Larissa, Biopolis- Larissa, Greece
    Recruiting
  • The Endocrine Unit of the University of Athens
    Athens, Greece
    Recruiting

Study contacts

  • Principal investigator: Eleni Zigkiri, PhD (c) — University of Thessaly
  • Study coordinator: Eleni Zigkiri, PhD (c)
  • Email: ezigkiri@uth.gr
  • Phone: +30 6878180765

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.