3D-Printed Hand Orthosis for ADL in Chronic Hand Conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In adults with chronic hand conditions, researchers compare a 3D-printed orthosis to a conventional plaster-cast orthosis to see how well each supports daily activities and hand function. The study builds on prior evidence suggesting similar outcomes but faster production and higher satisfaction with 3D-printed devices. Participants are adults requiring a circular thumb, wrist, or wrist-thumb orthosis for permanent use to aid everyday tasks. The design includes a direct comparison between the two orthosis types and considers cost-effectiveness alongside functional and quality-of-life measures. Conducted at Amsterdam UMC with support from ZonMw, the trial aims to provide robust data on feasibility, patient experience, and potential benefits of 3D printing in orthotic care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with a chronic, stable hand condition due to a neurological disorder, musculoskeletal disorder, neuromuscular disease or injury;
* Minimum age of 18 years;
* Indicated for a first or repeat prescription of a circular thumb, wrist or wrist-thumb orthosis for permanent use for improving ADL performance.

Exclusion Criteria:

* Indicated for an orthosis for a non-functional hand;
* Insufficient mastery of the Dutch language.

Where it's running

• Amsterdam UMC, location AMC
  Amsterdam, North Holland, Netherlands Recruiting

Study contacts

• Principal investigator: Merel-Anne Brehm, PhD — Amsterdam UMC, location AMC
• Study coordinator: Tanja Oud, PhD
• Email: t.a.oud@amsterdamumc.nl
• Phone: 31 20 5662615

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.