Finding the smallest effective dose of local anesthetic for shoulder surgery
Minimum Effective Local Anesthetic Volume of 0.5% Levobupivacaine Required for Ultrasound Guided Superior Trunk Block for Shoulder Surgery
This study is testing the smallest amount of a local anesthetic to see if it can effectively reduce pain for people having shoulder surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Shatin, New Territories) |
| Trial ID | NCT04941664 on ClinicalTrials.gov |
What this trial studies
This study aims to determine the minimum effective dosage of levobupivacaine needed to achieve a successful ultrasound-guided superior trunk block in patients undergoing shoulder arthroscopic surgery. By focusing on this specific nerve block, the research seeks to minimize postoperative pain while reducing the risk of complications associated with traditional anesthesia methods. The study will involve patients classified as ASA physical status I-III, ensuring a controlled and safe environment for the intervention. The ultimate goal is to establish a dosage that effectively blocks pain in at least 90% of participants.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled for elective upper shoulder arthroscopic rotator cuff repair who are classified as ASA physical status I-III.
Not a fit: Patients who may not benefit from this study include those who are pregnant, have a skin infection at the block site, or have a history of allergy to local anesthetics.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and reduced complications for patients undergoing shoulder surgeries.
How similar studies have performed: While there is limited data on the optimal volume for superior trunk blocks, similar studies on regional anesthesia techniques have shown promising results in improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I-III scheduled to undergo elective upper shoulder arthroscopic rotator cuff repair procedure Exclusion Criteria: * Patient refusal * pregnancy * skin infection at the site of block placement * history of allergy to local anaesthetic drugs * bleeding tendency or with evidence of coagulopathy * pre-existing neurological deficit or neuromuscular disease.
Where this trial is running
Shatin, New Territories
- Department of Anaesthesia & Intensive Care, Prince of Wales Hospital — Shatin, New Territories, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Manoj K Karmakar, MD — Chinese University of Hong Kong
- Study coordinator: Ayla Wong, RN, BN
- Email: aylawong@cuhk.edu.hk
- Phone: +85235056157
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.