Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Comparing two anesthesia techniques for upper extremity surgery

Official title: Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: A Randomized Superiority Trial Comparing Selective Trunk Block and Supraclavicular Brachial Plexus Block

Run by Chinese University of Hong Kong · NCT05649644 · Data updated 2026-11-12

This study is testing whether a new ultrasound-guided anesthesia technique can provide better pain relief and fewer side effects than the traditional method for people having surgery on their arms.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment50 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedMay 18, 2023
Main results expectedMay 31, 2027
Study endsJuly 31, 2027
Registry record updatedNovember 6, 2026
Trial IDNCT05649644 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are ASA 1-3 patients scheduled for elective or emergency upper extremity surgery.

Probably not a fit

Patients with pre-existing respiratory diseases or neurological deficits may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of ultrasound-guided Selective Trunk Block (SeTB) compared to the traditional Supraclavicular Brachial Plexus Block (BPB) for anesthesia during upper extremity surgeries. The research aims to determine if SeTB provides superior sensorimotor blockade and reduces the incidence of hemidiaphragmatic palsy. By analyzing the spread of anesthetic agents and their effects on major nerves, the study seeks to improve surgical outcomes and patient safety. Participants will be ASA 1-3 patients undergoing elective or emergency surgeries involving the upper extremity.

Why it matters

Potential benefit: If successful, this study could lead to safer and more effective anesthesia techniques for upper extremity surgeries, minimizing complications.

How similar studies have gone: While ultrasound-guided techniques have been widely studied, this specific comparison of SeTB and supraclavicular BPB is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA 1-3 patients
* Undergoing elective or emergency upper extremity surgery involving anywhere from the proximal humerus to distal hand or surgery involving any combination of these regions

Exclusion Criteria:

* Patient refusal
* Pregnancy
* Skin infection at the site of block placement
* History of allergy to local anaesthetic (LA) drugs
* Bleeding tendency or with evidence of coagulopathy
* Pre-existing respiratory disease
* Neurological deficit or neuromuscular disease.

Where it's running

  • Department of Anaesthesia & Intensive Care, Prince of Wales Hospital, Shatin, New Territories,
    Hong Kong, Hong Kong
    Recruiting

Study contacts

  • Principal investigator: Manoj K Karmakar, MD — Chinese University of Hong Kong
  • Study coordinator: Hoi Ling Wong, RN, BN
  • Email: aylawong@cuhk.edu.hk
  • Phone: +85255696157

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.