Comparing two anesthesia techniques for upper extremity surgery
Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: A Randomized Superiority Trial Comparing Selective Trunk Block and Supraclavicular Brachial Plexus Block
This study is testing whether a new ultrasound-guided anesthesia technique can provide better pain relief and fewer side effects than the traditional method for people having surgery on their arms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT05649644 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of ultrasound-guided Selective Trunk Block (SeTB) compared to the traditional Supraclavicular Brachial Plexus Block (BPB) for anesthesia during upper extremity surgeries. The research aims to determine if SeTB provides superior sensorimotor blockade and reduces the incidence of hemidiaphragmatic palsy. By analyzing the spread of anesthetic agents and their effects on major nerves, the study seeks to improve surgical outcomes and patient safety. Participants will be ASA 1-3 patients undergoing elective or emergency surgeries involving the upper extremity.
Who should consider this trial
Good fit: Ideal candidates are ASA 1-3 patients scheduled for elective or emergency upper extremity surgery.
Not a fit: Patients with pre-existing respiratory diseases or neurological deficits may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective anesthesia techniques for upper extremity surgeries, minimizing complications.
How similar studies have performed: While ultrasound-guided techniques have been widely studied, this specific comparison of SeTB and supraclavicular BPB is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-3 patients * Undergoing elective or emergency upper extremity surgery involving anywhere from the proximal humerus to distal hand or surgery involving any combination of these regions Exclusion Criteria: * Patient refusal * Pregnancy * Skin infection at the site of block placement * History of allergy to local anaesthetic (LA) drugs * Bleeding tendency or with evidence of coagulopathy * Pre-existing respiratory disease * Neurological deficit or neuromuscular disease.
Where this trial is running
Hong Kong
- Department of Anaesthesia & Intensive Care, Prince of Wales Hospital, Shatin, New Territories, — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Manoj K Karmakar, MD — Chinese University of Hong Kong
- Study coordinator: Hoi Ling Wong, RN, BN
- Email: aylawong@cuhk.edu.hk
- Phone: +85255696157
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.