Comparing two anesthesia techniques for upper extremity surgery
Official title: Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: A Randomized Superiority Trial Comparing Selective Trunk Block and Supraclavicular Brachial Plexus Block
Run by Chinese University of Hong Kong · NCT05649644 · Data updated 2026-11-12
This study is testing whether a new ultrasound-guided anesthesia technique can provide better pain relief and fewer side effects than the traditional method for people having surgery on their arms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | May 18, 2023 |
| Main results expected | May 31, 2027 |
| Study ends | July 31, 2027 |
| Registry record updated | November 6, 2026 |
| Trial ID | NCT05649644 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are ASA 1-3 patients scheduled for elective or emergency upper extremity surgery.
✕Probably not a fit
Patients with pre-existing respiratory diseases or neurological deficits may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of ultrasound-guided Selective Trunk Block (SeTB) compared to the traditional Supraclavicular Brachial Plexus Block (BPB) for anesthesia during upper extremity surgeries. The research aims to determine if SeTB provides superior sensorimotor blockade and reduces the incidence of hemidiaphragmatic palsy. By analyzing the spread of anesthetic agents and their effects on major nerves, the study seeks to improve surgical outcomes and patient safety. Participants will be ASA 1-3 patients undergoing elective or emergency surgeries involving the upper extremity.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective anesthesia techniques for upper extremity surgeries, minimizing complications.
How similar studies have gone: While ultrasound-guided techniques have been widely studied, this specific comparison of SeTB and supraclavicular BPB is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-3 patients * Undergoing elective or emergency upper extremity surgery involving anywhere from the proximal humerus to distal hand or surgery involving any combination of these regions Exclusion Criteria: * Patient refusal * Pregnancy * Skin infection at the site of block placement * History of allergy to local anaesthetic (LA) drugs * Bleeding tendency or with evidence of coagulopathy * Pre-existing respiratory disease * Neurological deficit or neuromuscular disease.
Where it's running
-
Department of Anaesthesia & Intensive Care, Prince of Wales Hospital, Shatin, New Territories,
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Manoj K Karmakar, MD — Chinese University of Hong Kong
- Study coordinator: Hoi Ling Wong, RN, BN
- Email: aylawong@cuhk.edu.hk
- Phone: +85255696157
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.