Observing kidney diseases related to the immune system
Studies of Immunologically-Mediated Kidney Diseases
This study is trying to learn more about kidney diseases caused by the immune system in patients to find better treatments and understand how these conditions develop.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 10 Years to 99 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT00001979 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients with immunologically-mediated kidney diseases such as nephrotic syndrome, glomerulonephritis, and lupus nephritis. Participants will undergo thorough evaluations, including history, physical examinations, and laboratory tests, to better understand the causes and characteristics of these conditions. Blood and urine samples will be collected for further immunological research, aiming to identify potential biomarkers and improve treatment responses. The study will also explore the natural history and complications associated with these diseases.
Who should consider this trial
Good fit: Ideal candidates include adults and children aged 10-17 with known or suspected immunologically-mediated kidney diseases.
Not a fit: Patients with unrelated medical conditions that could confound the study results may not benefit from participation.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients with autoimmune kidney diseases.
How similar studies have performed: Other studies have shown success in characterizing immunologically-mediated kidney diseases, indicating that this approach has potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, a participant must meet all of the following criteria: 1. Adults \>= 18 years of age and children 10-17 years of age 2. Participants with 1. known, proven, or suspected immunologically-mediated kidney diseases, including but not limited to nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with other systemic or connective tissue disorders, OR 2. immunologically-mediated diseases with the potential for kidney disease. 3. Ability of the participant or guardian to understand and the willingness of the participant or guardian to provide written informed consent. EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Concomitant medical problems which would confound the interpretation of studies of the immunologic kidney disorder. 2. Concomitant medical, surgical, or other conditions for which inadequate facilities or funds are available to support their care at the NIH.
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Meryl A Waldman, M.D. — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Study coordinator: Meryl A Waldman, M.D.
- Email: waldmanm@mail.nih.gov
- Phone: (301) 451-6990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.