Mineral-infused clothing to help muscles recover after hard exercise

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-site, randomized, double-blind, sham-controlled study compares a mineral-infused recovery garment to an identical non-mineral garment in adults aged 18–45 who have not done recent lower-body training. Participants perform a 100-drop-jump protocol to induce muscle damage, then wear the assigned garment for 72 hours and undergo repeated testing of knee-extensor strength, jump performance, soreness, and blood markers of muscle damage. Primary and secondary outcomes include maximal voluntary isometric contraction strength at 72 hours, recovery of jump performance, soreness ratings, and creatine kinase levels, with comfort and tolerability recorded as well. The trial uses remote screening and a fixed order of baseline assessments, followed by in-person testing on four consecutive days at one Exeter site. The garment’s external specifications are matched between groups to ensure blinding.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 45 years inclusive
* Body mass index between 18.5 and 29.9 kg/m2 inclusive
* No participation in structured lower-limb resistance training or plyometric (jump) training within the previous 6 months (structured training: a planned programme of exercise against external load or bodyweight loading targeting the lower limbs, performed at least once per week for 4 or more consecutive weeks)
* No history of injury that may impair the ability to perform maximal exercise
* Willing to wear the allocated study garment for a minimum of 16 hours per day (approximately 8 hours waking and 8 hours overnight) throughout the 72-hour post-exercise recovery period, and during the muscle-damaging exercise protocol
* Willing to maintain habitual diet and physical activity, including usual caffeine intake; to have the last meal and any caffeine at least 2 hours before each testing session; and to abstain from alcohol throughout the trial
* Able to attend the study site on four consecutive days
* Able to provide written informed consent
* Able to read, understand and communicate in English
* Currently living in the United Kingdom

Exclusion Criteria:

* Current use of non-steroidal anti-inflammatory drugs, corticosteroids or other anti-inflammatory medication
* Current use of statins
* Use of dietary supplements with known anti-inflammatory or antioxidant activity
* Diagnosed muscle, neuromuscular or connective tissue disorders
* Bleeding disorders or current use of anticoagulant medication
* Known allergy or sensitivity to any material used in the study garment, or a history of textile or contact dermatitis
* Pregnancy, breastfeeding, or intention to become pregnant during the study period
* Current participation, or participation within 4 weeks of screening, in another interventional clinical trial
* Any condition that, in the opinion of the investigator, would compromise participant safety or data integrity
* Current use, or use within 4 weeks, of any form of compression garment
* Any response to the general health questions in the Screening Questionnaire indicating a contraindication to maximal exercise

Where it's running

• StudySetGo
  Exeter, United Kingdom Recruiting

Study contacts

• Principal investigator: Tom Jameson, PhD — StudySetGo Ltd
• Study coordinator: Christopher Koscien, PhD
• Email: perfict@studysetgo.com
• Phone: +447847617414

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.