5-week Lactobacillus casei probiotic to reduce post-exercise muscle soreness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy, physically active young adults will take either a Lactobacillus casei probiotic or a placebo capsule for five weeks and complete an exercise protocol that induces muscle damage. Researchers will compare perceived muscle soreness, pressure pain threshold, and power output after the exercise to see if the probiotic group recovers faster or reports less soreness. Participants must be free of injuries and major medical conditions and able to abstain from consistent NSAID use and other probiotics during the study. The intervention is administered at a single center with in-person testing before and after the exercise-induced muscle damage protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month
* good general health with no injuries or health conditions that would affect physical activity
* willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study

Exclusion Criteria:

* known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required
* underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases
* currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window
* report using an NSAID more than twice a week on a regular basis

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Mary Stenson — University of Minnesota
• Study coordinator: Jakob Fischer
• Email: fisc0887@d.umn.edu
• Phone: 507-236-8051

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.