Acute Cryotherapy on Musculoskeletal Function
Official title: Effects of Acute Cryotherapy on Musculoskeletal Function and Biomarkers for Inflammation, Oxidative Stress, and Muscle Damage
Run by University of Texas, El Paso · NCT07211412 · Data updated 2026-11-12
This study tests whether applying a daily cold-pack after eccentric exercise helps reduce muscle damage and improve function in healthy people.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Texas, El Paso Academic / other |
| Locations | 1 site (El Paso, Texas) |
| Status | Recruiting |
| Started | November 15, 2025 |
| Main results expected | December 15, 2027 |
| Study ends | May 15, 2028 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07211412 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults who are normotensive, non-smokers, and without recent musculoskeletal injury or cardiovascular disease.
✕Probably not a fit
Individuals with cardiovascular conditions, pregnancy, recent injuries, or other excluded conditions may not benefit and could be at risk.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, double-blind, controlled trial compares three groups: a no-exercise/no-cryotherapy control, an exercise with room-temperature cooling, and an exercise with daily cryotherapy for 15 minutes. Outcomes include functional measures and blood biomarkers collected at multiple time points up to about 11 days after exercise. The study uses a two-way ANOVA to analyze time and group effects on the measured endpoints.
Why it matters
Potential benefit: If successful, cryotherapy after intense exercise could help lessen muscle damage and speed recovery.
How similar studies have gone: Previous work in cryotherapy and acute muscle injury has shown mixed results, making this trial's randomized design important to clarify potential benefits.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * apparently healthy * normotensive * non-smokers (all tobacco products including e-cigarettes) Exclusion Criteria: * Cardiovascular diseases (including hypertension) * pregnancy * any musculoskeletal injury 6 months prior the study
Where it's running
-
The University of Texas at El Paso, Rehabilitation Sciences Complex
El Paso, Texas, United States Recruiting
Study contacts
- Study coordinator: Alvaro N Gurovich, PT, PhD
- Email: agurovich@utep.edu
- Phone: 915-747-7248
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.