Measuring follicular volume to improve oocyte maturation in women with low ovarian reserve
Official title: Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Run by ART Fertility Clinics LLC · NCT06839274 · Data updated 2026-11-12
This study is testing if measuring the size of ovarian follicles can help women with low egg supply get healthier eggs during fertility treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 48 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | ART Fertility Clinics LLC Academic / other |
| Locations | 1 site (Abu Dhabi, Abu Dhabi Emirate) |
| Status | Recruiting |
| Started | March 27, 2025 |
| Main results expected | December 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | June 25, 2026 |
| Trial ID | NCT06839274 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include women aged 18-48 with a severely diminished ovarian reserve undergoing IVF or ICSI with preimplantation genetic testing.
✕Probably not a fit
Patients who have surgically retrieved sperm or do not meet the inclusion criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on women with severely diminished ovarian reserve who are undergoing ovarian stimulation for oocyte vitrification. It aims to assess the correlation between follicular volume at the time of final oocyte maturation and oocyte maturity. By measuring follicular volume alongside traditional metrics, the study seeks to establish a cutoff value that could help optimize the timing of trigger administration, potentially reducing the risk of premature ovulation and improving the chances of obtaining mature oocytes. The intervention involves transvaginal ultrasound to accurately measure follicular volume.
Why it matters
Potential benefit: If successful, this approach could enhance the chances of achieving mature oocytes and viable embryos for women with low ovarian reserve.
How similar studies have gone: While this approach is innovative, similar studies have shown that optimizing trigger timing can improve outcomes in patients with low ovarian reserve.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Reproductive age group: 18 -48 * undergoing ovarian stimulation for oocyte vetrification * undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr * less than or equal to 3 AFC on initiation of stimulation * follicular phase stimulation Exclusion Criteria: * surgically retrieved sperm
Where it's running
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ART Fertility Clinics
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates Recruiting
Study contacts
- Study coordinator: Jonalyn Edades, MBA
- Email: jonalyn.edades@artfertilityclinics.com
- Phone: +97126528000
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.