Clinical trial Recruiting at 1 site Observational Ages 18 to 48 Women only

Measuring follicular volume to improve oocyte maturation in women with low ovarian reserve

Official title: Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity

Run by ART Fertility Clinics LLC · NCT06839274 · Data updated 2026-11-12

This study is testing if measuring the size of ovarian follicles can help women with low egg supply get healthier eggs during fertility treatment.

More Ovarian Stimulation trials

Quick facts

Study typeObservational
Ages18 Years to 48 Years
SexWomen only
Enrollment100 (estimated)
SponsorART Fertility Clinics LLC
Academic / other
Locations1 site (Abu Dhabi, Abu Dhabi Emirate)
StatusRecruiting
StartedMarch 27, 2025
Main results expectedDecember 30, 2026
Study endsDecember 31, 2026
Registry record updatedJune 25, 2026
Trial IDNCT06839274 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include women aged 18-48 with a severely diminished ovarian reserve undergoing IVF or ICSI with preimplantation genetic testing.

Probably not a fit

Patients who have surgically retrieved sperm or do not meet the inclusion criteria may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on women with severely diminished ovarian reserve who are undergoing ovarian stimulation for oocyte vitrification. It aims to assess the correlation between follicular volume at the time of final oocyte maturation and oocyte maturity. By measuring follicular volume alongside traditional metrics, the study seeks to establish a cutoff value that could help optimize the timing of trigger administration, potentially reducing the risk of premature ovulation and improving the chances of obtaining mature oocytes. The intervention involves transvaginal ultrasound to accurately measure follicular volume.

Why it matters

Potential benefit: If successful, this approach could enhance the chances of achieving mature oocytes and viable embryos for women with low ovarian reserve.

How similar studies have gone: While this approach is innovative, similar studies have shown that optimizing trigger timing can improve outcomes in patients with low ovarian reserve.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Reproductive age group: 18 -48
* undergoing ovarian stimulation for oocyte vetrification
* undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr
* less than or equal to 3 AFC on initiation of stimulation
* follicular phase stimulation

Exclusion Criteria:

* surgically retrieved sperm

Where it's running

  • ART Fertility Clinics
    Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.