Monitoring FSH levels to optimize ovarian stimulation
Official title: Assessment of the Role of Serum FSH Monitoring During Ovarian Stimulation and Identification of an Optimal Range for Expected Normal Responders
Run by ART Fertility Clinics LLC · NCT06572930 · Data updated 2026-11-12
This study is testing if keeping track of FSH hormone levels can help improve the success of ovarian stimulation for women trying to conceive.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 39 Years |
| Sex | Women only |
| Enrollment | 150 (estimated) |
| Sponsor | ART Fertility Clinics LLC Academic / other |
| Locations | 1 site (Abu Dhabi, Abu Dhabi Emirate) |
| Status | Recruiting |
| Started | December 16, 2024 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | June 25, 2026 |
| Trial ID | NCT06572930 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 21 to 39 with regular menstrual cycles, a specific BMI range, and certain ovarian reserve indicators.
✕Probably not a fit
Patients with conditions such as hypogonadotropic hypogonadism, history of ovarian surgery, or those older than 39 years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the role of serum Follicle Stimulating Hormone (FSH) levels in predicting oocyte yield and progesterone levels during ovarian stimulation. It considers various factors such as age, baseline FSH, Antral Mullerian Hormone (AMH), antral follicle count, body weight, kidney function, and urinary FSH. The goal is to identify a minimum FSH level that ensures optimal ovarian response, allowing for tailored FSH dosages to improve outcomes. By focusing on FSH monitoring, the study aims to enhance the effectiveness of ovarian stimulation protocols.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective ovarian stimulation protocols, improving fertility outcomes for patients.
How similar studies have gone: While the approach of monitoring FSH levels is not widely tested, similar studies have shown promise in optimizing ovarian stimulation protocols.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * regular 21 - 35 days cycles * BMI between 19 - 30 kg/m2 * serum AMH level between 1.5 to 3 ng/ml * a total antral follicle count between 10 to 24 * endogenous early follicular phase serum FSH level \<10 IU/L * normal glomerular filtration rate Exclusion Criteria: * hypogonadotropic hypogonadism * history of ovarian surgery * permanent ovarian cysts of any form * older than 39 years * abnormal thyroid stimulating hormone (TSH) * renal disease * elevated prolactin levels * intake of oral contraceptives 3 months before stimulation start and estradiol pretreatment will be excluded
Where it's running
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ART Fertility Clinics
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates Recruiting
Study contacts
- Study coordinator: Jonalyn Edades
- Email: jonalyn.edades@artfertilityclinics.com
- Phone: +971526408688
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This trial tests whether an AI program can guide monitoring and the ovulation trigger to produce similar or better IVF cycle results than decisions made by doctors.
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Measuring follicular volume to improve oocyte maturation in women with low ovarian reserve
This study is testing if measuring the size of ovarian follicles can help women with low egg supply get healthier eggs during fertility treatment.
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rFSH versus hMG effects on cumulus cell telomere length and blastocyst development
This trial will test whether using recombinant FSH (Gonal‑F) versus human menopausal gonadotropin (Menopur) during ovarian stimulation changes cumulus cell telomere length and later blastocyst outcomes in women 18–38 undergoing IVF with PGT‑A.
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Progestin-primed ovarian stimulation with corifollitropin alfa versus standard rFSH/GnRH antagonist (crossover)
This study will test whether progestin-primed ovarian stimulation using a single-dose corifollitropin alfa improves patient satisfaction and compliance while producing similar ovarian response compared with conventional recombinant FSH plus a GnRH antagonist in women having their first IVF/ICSI cycle for fertility pres
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.