Clinical trial Recruiting at 1 site Observational Ages 18 to 39 Women only

Monitoring FSH levels to optimize ovarian stimulation

Official title: Assessment of the Role of Serum FSH Monitoring During Ovarian Stimulation and Identification of an Optimal Range for Expected Normal Responders

Run by ART Fertility Clinics LLC · NCT06572930 · Data updated 2026-11-12

This study is testing if keeping track of FSH hormone levels can help improve the success of ovarian stimulation for women trying to conceive.

Quick facts

Study typeObservational
Ages18 Years to 39 Years
SexWomen only
Enrollment150 (estimated)
SponsorART Fertility Clinics LLC
Academic / other
Locations1 site (Abu Dhabi, Abu Dhabi Emirate)
StatusRecruiting
StartedDecember 16, 2024
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedJune 25, 2026
Trial IDNCT06572930 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 21 to 39 with regular menstrual cycles, a specific BMI range, and certain ovarian reserve indicators.

Probably not a fit

Patients with conditions such as hypogonadotropic hypogonadism, history of ovarian surgery, or those older than 39 years may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the role of serum Follicle Stimulating Hormone (FSH) levels in predicting oocyte yield and progesterone levels during ovarian stimulation. It considers various factors such as age, baseline FSH, Antral Mullerian Hormone (AMH), antral follicle count, body weight, kidney function, and urinary FSH. The goal is to identify a minimum FSH level that ensures optimal ovarian response, allowing for tailored FSH dosages to improve outcomes. By focusing on FSH monitoring, the study aims to enhance the effectiveness of ovarian stimulation protocols.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective ovarian stimulation protocols, improving fertility outcomes for patients.

How similar studies have gone: While the approach of monitoring FSH levels is not widely tested, similar studies have shown promise in optimizing ovarian stimulation protocols.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* regular 21 - 35 days cycles
* BMI between 19 - 30 kg/m2
* serum AMH level between 1.5 to 3 ng/ml
* a total antral follicle count between 10 to 24
* endogenous early follicular phase serum FSH level \<10 IU/L
* normal glomerular filtration rate

Exclusion Criteria:

* hypogonadotropic hypogonadism
* history of ovarian surgery
* permanent ovarian cysts of any form
* older than 39 years
* abnormal thyroid stimulating hormone (TSH)
* renal disease
* elevated prolactin levels
* intake of oral contraceptives 3 months before stimulation start and estradiol pretreatment will be excluded

Where it's running

  • ART Fertility Clinics
    Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.